Citation: Ming GUO, Qing Sen YU, Jian Wei YAN, Fei TAN, Guo Zheng MA. Characterization of the Interaction between Bovine Serum Albumin and Lomefloxacin by Capillary Zone Electrophoresis[J]. Chinese Chemical Letters, ;2004, 15(11): 1331-1334. shu

Characterization of the Interaction between Bovine Serum Albumin and Lomefloxacin by Capillary Zone Electrophoresis

1.
Department of Chemistry, Zhejiang University, Hangzhou 3100271;
2.
Department of Chinese Medicine Science & Engineering, Zhejiang University, Hangzhou 3100271

Received Date: 20 October 2003

Fund Project: This work was supported by the NNSFC (grant number 20173050). The authors gratefully acknowledge for this financial support.

Three capillary zone electrophoresis (CZE) methods of the frontal analysis (FA), vacancy peak (VP) and simplified Hummel-Dreyer (SHD) were applied to investigate interaction between bovine serum albumin (BSA) and lomefloxacin, the experimental condition was established after a large number of tests. Based on the site-binding model, the binding parameters were measured according to the site model by Scatchard.
- CZE,
- the site model,
- BSA,
- lomefloxacin
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