Citation: Han LIANG, Jing Jian LI, Xiao Dong LI, Fei Li TANG, Gu YUAN. Study on the Interaction between Distamycin Analogs and DNA from Herring Sperm by Fluorimetry[J]. Chinese Chemical Letters, ;2002, 13(10): 1001-1002. shu

Study on the Interaction between Distamycin Analogs and DNA from Herring Sperm by Fluorimetry

1.
Department of Chemistry, Peking University, Beijing 100871;
2.
The Key Laboratory of Bioorganic Chemistry and Molecular Engineering, Department of Chemical Biology, Peking University, Beijing 100871

Received Date: 16 January 2002

Fund Project: The project was supported by the National Natural Science Foundation of China (No.39970169, 29872001).

The fluorescence spectra of the interaction between four new distamycin analogs and DNA from herring sperm have been studied in detail. The fluorescence quenching of the DNA by the analogs was observed, and the fluorescence intensity of the DNA was attenuated exponentially with the increasing of the analogs concentration.
- Distamycin analogs,
- fluorescence quenching,
- DNA from herring sperm
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