Citation: Shi Detai, He Xiaopeng. Albumin: A Multifunctional Carrier for Cancer Theranostics[J]. Chemistry, ;2020, 83(3): 195-208. shu

Albumin: A Multifunctional Carrier for Cancer Theranostics

Shi Detai ^1,2 ,
He Xiaopeng ^1,,

1.
Key Laboratory for Advanced Materials, Feringa Nobel Prize Scientist Joint Research Center, School of Chemistry and Molecular Engineering, East China University of Science and Technology, Shanghai, 200237
2.
School of Materials Science and Engineering, Jingdezhen Ceramic Institute, Jingdezhen, 333403

Corresponding author: He Xiaopeng, xphe@ecust.edu.cn
Received Date: 1 December 2019
Accepted Date: 23 December 2019

Figures(10)

Serum albumin has a long circulatory half-life in blood, and can be actively internalized by tumor cells through albumin receptor-mediated pathways. Consequently, this natural biomacromolecule has been recognized as one of the most promising carriers for building theranostic agents. Multifunctional albumin carriers have been used for conjugation with a variety of imaging agents and therapeutic agents towards cancer theranostics. Both covalent and non-covalent strategies have been developed for albumin functionalization. In this review, we summarize the recent progress and propose future perspectives in regard to the exploitation of albumin carriers for precision cancer theranostics.
- Serum albumin,
- Carriers,
- Antitumor,
- Theranostics
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