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Citation: Li Hang, Zhou Bo, Wang Jun, Gong Wei, Yin Xiaogang. Catalytic Synthesis of α-Amino Nitrile Derivatives by
Hydrotalcite-Supported Iodine[J]. Chemistry, ;2020, 83(5): 472-475. shu

Catalytic Synthesis of α-Amino Nitrile Derivatives by
Hydrotalcite-Supported Iodine

School of Chemistry and Materials Science, Guizhou Normal University, Guizhou Key Laboratory of Functional Materials Chemistry, Guiyang, 550001

Corresponding author: Yin Xiaogang, m13885115516@163.com
Received Date: 2 December 2019
Accepted Date: 25 February 2020

Figures(1)

Using hydrotalcite supported iodine (I₂/LDHs) as catalyst, aromatic aldehyde, aromatic amine and trimethylsilycyanide (TMSCN) as raw material, 10 kinds of alpha amino acrylic derivatives were synthesized, and their structures are confirmed by ¹H NMR. Under the optimum reaction conditions:n_benzaldehyde:n_aniline:n_TMSCN=1.0:1.0:1.4, hydrotalcite supported iodine (10(mol)%) as catalyst, methanol as solvent, and stirred for 10 minutes. The highest yield of α-aminonitriles can reach 98.3%.
- Aromatic aldehyde,
- Aromatic amine,
- I₂/LDHs
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Catalytic Synthesis of α-Amino Nitrile Derivatives by Hydrotalcite-Supported Iodine

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通讯作者: 陈斌, bchen63@163.com

Catalytic Synthesis of α-Amino Nitrile Derivatives by
Hydrotalcite-Supported Iodine