Citation: Xian Hong YIN, Man Ya YANG, Hua Hong SHI, Lian Quan GU. Synthesis of Isoquinoline-1, 3-Dicarboxylic Acid[J]. Chinese Chemical Letters, ;1999, 10(11): 907-910. shu

Synthesis of Isoquinoline-1, 3-Dicarboxylic Acid

1.
Chemistry Department Zhongshan University Guangzhou 510275;
2.
Chemistry Department Guangxin University for Nationalities Nanning 530006

Received Date: 15 June 1999

Fund Project: We gratefully acknowledge support of this work by the National Natural Science Foundation of China (grant 29701006 to HHS) and the Natural Science Foundation of Guangdong Province (grant 960001 to HHS). Many thanks to Professor Frederick S. Richardson of the University of Virginia for his kind help.

Two new compounds, isoquinoline-1, 3-dicarboxyaldehyde and (IDA) were synthesized via 6 or 7 steps starting from benzaldehyde, or prepared via 4 steps starting from allylbenzene.
- Beckman rearrangement reaction,
- intramolecular electrophilic substitution,
- 1.3-dimethyl-isoquinoline derivatives
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