Citation: Jiang Daofa, Yang Xinan, Jin Yanmei, Gao Jie, Zhao Weiwei, Ma Peihua. Identification of Human Amino Acids by A Novel Host-Guest Fluorescent Probe[J]. Chemistry, ;2020, 83(9): 813-820. shu

Identification of Human Amino Acids by A Novel Host-Guest Fluorescent Probe

Key Laboratory of Macrocyclic Chemistry and Supramolecular Chemistry of Guizhou Province, Guizhou University, Guiyang, 550025

Corresponding author: Ma Peihua, phma@gzu.edu.cn
Received Date: 15 January 2020
Accepted Date: 30 April 2020

Figures(10)

In this paper, the host-guest interaction of cyclopentyl substituted cucurbit[6]uril (CyP₆Q[6]) and 2-(β-pyridine)-1H-imidazole [4, 5-f] [1, 10] phenanthroline hydrochloride(Ar-IPHS) was studied, and a fluorescent probe Ar-IPHS@CyP₆Q[6] was prepared to identify amino acids by utilizing the property that CyP₆Q[6] can make Ar-IPHS produce strong fluorescence. The experimental results showed that the probe can efficiently identify glycine, lysine, and methionine with detection limit of 2.27×10^-6 mol/L, 1.359×10^-5 mol/L, and 1.690×10^-5 mol/L, respectively.
- Probe,
- Amino acids,
- Identification
1. [1]
  Chalova V I, Zabala-Díaz I B, Woodward C L, et al. World. J. Microbiol. Biotechnol., 2008, (24): 353～359.
2. [2]
  Shahrokhian S. Anal. Chem., 2001, 73(24): 5972～5978.
3. [3]
  Guthrie R, Susi A. Pediatrics, 1963, 32(3): 338～343.
4. [4]
  Fisher G H, Arias I, Quesada I, et al. Amino Acids, 2001, 20: 163～173.
5. [5]
  Jones D L, Owen A G, Farrar J F, et al. Soil Biol. Biochem., 2002, 34: 1893～1902.
6. [6]
  Chace D H, Kalas T A, Naylor E W. Clin. Chem., 2003, 49 (11): 1797～1817.
7. [7]
  Sarwar G, Botting H G. J. Chromatogr. Biomed. Appl., 1993, 615(1): 1～22.
8. [8]
  Kim M I, Park T J, Heo N S, et al. Anal. Chem., 2014, 86(5): 2489～2496.
9. [9]
  Liu Z S, Craven C B, Huang G, et al. Anal. Chem., 2019, 91(20): 13213～13221.
10. [10]
  Yao Z P, Wan T S M, Kwong K P, et al. Anal. Chem., 2000, 72(21): 5383～5393.
11. [11]
  Mahsa M, Mohammad G, Mohammad C, et al. Spectrochim. Acta A, 2012, 96: 801～804.
12. [12]
  Ojida A, Mito-oka Y, Sada K, et al. J. Am. Chem. Soc., 2004, 126: 2454～2463.
13. [13]
  Zhao D, Chan W H, He Z K, et al. Anal. Chem., 2009, 81: 3537～3543.
14. [14]
  Lin V S Y, Lai C Y, Huang J G, et al. J. Am. Chem. Soc., 2001, 123: 11510～11511.
15. [15]
16. [16]
  Anand T, Sivaraman G, Iniya M, et al. Anal. Chim. Acta, 2015, 876: 1～8.
17. [17]
  Motesharei K, Myles D C. J. Am. Chem. Soc., 1994, 116: 7413～7414.
18. [18]
  Jhaveri S D, Kirby R, Conrad R, et al. J. Am. Chem. Soc., 2000, 122: 2469～2473
19. [19]
  Albelda T, Bernardo A, Garcia-España E, et al. J. Chem. Soc. Perkin Transac., 1999, 2: 2545～2549.
20. [20]
  Hamasaki K, Ikeda H, Nakamura A, et al. J. Am. Chem. Soc., 1993, 115: 5035～5040.
21. [21]
  Nutiu R, Li Y F. Chem. Eur. J., 2004, 10: 1868～1876.
22. [22]
  Zhu Y Y, Wu X D, Gu S X, et al. J. Am. Chem. Soc., 2019, 141 (1): 175～181.
23. [23]
  Wang Q, Wu X D, Pu L. Org. Lett., 2019, 21 (22): 9036～9039.
24. [24]
  Jiang Y Y, Liu C X, Wang X Q, et al. Langmuir, 2017, 33 (29): 7239～7247.
25. [25]
  Kaifer A E. Acc. Chem. Res., 2014, 47: 2160～2167.
26. [26]
  Ghale G, Nau W M. Acc. Chem. Res., 2014, 47: 2150～2159.
27. [27]
  Ghosh I, Nau W M. Adv. Drug. Deliver. Rev., 2014, 64: 764～738.
28. [28]
  Wang X L, Chen Y Q, Gao Q, et al. Cryst. Growth Design, 2010, 10(5): 2174～2184.
29. [29]
  Wu F, Wu L H, Xiao X, et al. J. Org. Chem., 2012, 77 (1): 606～611.
1. [1]
  Hong CAI , Jiewen WU , Jingyun LI , Lixian CHEN , Siqi XIAO , Dan LI . Synthesis of a zinc-cobalt bimetallic adenine metal-organic framework for the recognition of sulfur-containing amino acids. Chinese Journal of Inorganic Chemistry, 2025, 41(1): 114-122. doi: 10.11862/CJIC.20240382
2. [2]
  Runjie Li , Hang Liu , Xisheng Wang , Wanqun Zhang , Wanqun Hu , Kaiping Yang , Qiang Zhou , Si Liu , Pingping Zhu , Wei Shao . 氨基酸的衍生及手性气相色谱分离创新实验. University Chemistry, 2025, 40(6): 286-295. doi: 10.12461/PKU.DXHX202407059
3. [3]
  Yang Wang , Yunpeng Fu , Xiaoji Liu , Guotao Zhang , Guobin Li , Wanqiang Liu , Jinglun Wang . Structural Analysis of Nitrile Solutions Based on Infrared Spectroscopy Probes. University Chemistry, 2025, 40(4): 367-374. doi: 10.12461/PKU.DXHX202406113
4. [4]
  Ruiying WANG , Hui WANG , Fenglan CHAI , Zhinan ZUO , Benlai WU . Three-dimensional homochiral Eu(Ⅲ) coordination polymer and its amino acid configuration recognition. Chinese Journal of Inorganic Chemistry, 2025, 41(5): 877-884. doi: 10.11862/CJIC.20250052
5. [5]
  Jinlong YAN , Weina WU , Yuan WANG . A simple Schiff base probe for the fluorescent turn-on detection of hypochlorite and its biological imaging application. Chinese Journal of Inorganic Chemistry, 2024, 40(9): 1653-1660. doi: 10.11862/CJIC.20240154
6. [6]
  Renjie Xue , Chao Ma , Jing He , Xuechao Li , Yanning Tang , Lifeng Chi , Haiming Zhang . Catassembly in the Host-Guest Recognition of 2D Metastable Self-Assembled Networks. Acta Physico-Chimica Sinica, 2024, 40(9): 2309011-0. doi: 10.3866/PKU.WHXB202309011
7. [7]
  Peiran ZHAO , Yuqian LIU , Cheng HE , Chunying DUAN . A functionalized Eu³⁺ metal-organic framework for selective fluorescent detection of pyrene. Chinese Journal of Inorganic Chemistry, 2024, 40(4): 713-724. doi: 10.11862/CJIC.20230355
8. [8]
  Jinghan ZHANG , Guanying CHEN . Progress in the application of rare-earth-doped upconversion nanoprobes in biological detection. Chinese Journal of Inorganic Chemistry, 2024, 40(12): 2335-2355. doi: 10.11862/CJIC.20240249
9. [9]
  Yingpeng ZHANG , Xingxing LI , Yunshang YANG , Zhidong TENG . A pyrazole-based turn-off fluorescent probe for visual detection of hydrazine. Chinese Journal of Inorganic Chemistry, 2025, 41(7): 1301-1308. doi: 10.11862/CJIC.20250064
10. [10]
  Yuting DU , Jing YUAN , Peiyao DENG . Synthesis and application of a fluorescent probe for the detection of reduced glutathione. Chinese Journal of Inorganic Chemistry, 2025, 41(7): 1331-1337. doi: 10.11862/CJIC.20240461
11. [11]
  Mengyang LI , Hao XU , Zhonghao NIU , Chunhua GONG , Weihui ZHONG , Jingli XIE . Highly effective catalytic synthesis of β-amino alcohols by using viologen-polyoxometalate hybrid materials. Chinese Journal of Inorganic Chemistry, 2025, 41(7): 1294-1300. doi: 10.11862/CJIC.20250080
12. [12]
  Jiakun BAI , Ting XU , Lu ZHANG , Jiang PENG , Yuqiang LI , Junhui JIA . A red-emitting fluorescent probe with a large Stokes shift for selective detection of hypochlorous acid. Chinese Journal of Inorganic Chemistry, 2024, 40(6): 1095-1104. doi: 10.11862/CJIC.20240002
13. [13]
  Qi Wang , Yicong Gao , Feng Lu , Quli Fan . Preparation and Performance Characterization of the Second Near-Infrared Phototheranostic Probe: A New Design and Teaching Practice of Polymer Chemistry Comprehensive Experiment. University Chemistry, 2024, 39(11): 342-349. doi: 10.12461/PKU.DXHX202404141
14. [14]
  Jun LUO , Baoshu LIU , Yunchang ZHANG , Bingkai WANG , Beibei GUO , Lan SHE , Tianheng CHEN . Europium(Ⅲ) metal-organic framework as a fluorescent probe for selectively and sensitively sensing Pb²⁺ in aqueous solution. Chinese Journal of Inorganic Chemistry, 2024, 40(12): 2438-2444. doi: 10.11862/CJIC.20240240
15. [15]
  Pingping LU , Shuguang ZHANG , Peipei ZHANG , Aiyun NI . Preparation of zinc sulfate open frameworks based probe materials and detection of Pb²⁺ and Fe³⁺ ions. Chinese Journal of Inorganic Chemistry, 2025, 41(5): 959-968. doi: 10.11862/CJIC.20240411
16. [16]
  Yanxi LIU , Mengjia XU , Haonan CHEN , Quan LIU , Yuming ZHANG . A fluorescent-colorimetric probe for peroxynitrite-anion-imaging in living cells. Chinese Journal of Inorganic Chemistry, 2025, 41(6): 1112-1122. doi: 10.11862/CJIC.20240423
17. [17]
  Benhua Wang , Chaoyi Yao , Yiming Li , Qing Liu , Minhuan Lan , Guipeng Yu , Yiming Luo , Xiangzhi Song . 一种基于香豆素氟离子荧光探针的合成、表征及性能测试——“科研反哺教学”在有机化学综合实验教学中的探索与实践. University Chemistry, 2025, 40(6): 201-209. doi: 10.12461/PKU.DXHX202408070
18. [18]
  Qingying Gao , Tao Luo , Jianyuan Su , Chaofan Yu , Jiazhu Li , Bingfei Yan , Wenzuo Li , Zhen Zhang , Yi Liu . Refinement and Expansion of the Classic Cinnamic Acid Synthesis Experiment. University Chemistry, 2024, 39(5): 243-250. doi: 10.3866/PKU.DXHX202311074
19. [19]
  Lanjun Cheng , Xinyuan Wang , Jie An , Xiang Wu , Chengfeng Zhu , Yanming Fu , Yougui Li . Improvement of the Resolution Experiment of Racemic Tartaric Acid. University Chemistry, 2025, 40(7): 277-285. doi: 10.12461/PKU.DXHX202408010
20. [20]
  Yongqing Kuang , Jie Liu , Jianjun Feng , Wen Yang , Shuanglian Cai , Ling Shi . Experimental Design for the Two-Step Synthesis of Paracetamol from 4-Hydroxyacetophenone. University Chemistry, 2024, 39(8): 331-337. doi: 10.12461/PKU.DXHX202403012

Get Citation

PDF

XML

Metrics

PDF Downloads(12)
Abstract views(1669)
HTML views(502)

通讯作者: 陈斌, bchen63@163.com

1.
沈阳化工大学材料科学与工程学院沈阳 110142