Citation: Meng Yuzhang, Gao Yuxia, Ju Yong, Hu Jun. Natural Pentacyclic Triterpene-based Organic Functional Molecules[J]. Chemistry, ;2020, 83(4): 318-324. shu

Natural Pentacyclic Triterpene-based Organic Functional Molecules

Meng Yuzhang ¹ ,
Gao Yuxia ² ,
Ju Yong ³ ,
Hu Jun ^1,,

1.
Bejing Advanced Innovation Center for Soft Matter Science and Engineering, Beijing University of Chemical Technology, Beijing, 100029
2.
College of Science, China Agricultural University, Beijing, 100193
3.
Key Laboratory of Bioorganic Phosphorus Chemistry and Chemical Biology, Ministry of Education, Department of Chemistry, Tsinghua University, Beijing, 100084

Corresponding author: Hu Jun, jhu@mail.buct.edu.cn
Received Date: 6 December 2019
Accepted Date: 16 December 2019

Figures(13)

Terpenes, isolated from plants and animals, have been widely found in nature. They can be divided into cyclic-, linear-, and polycyclic terpenes according to the number of isoprene units and skeleton rings in their molecular structures. Among them, natural triterpenes are one of the ideal building blocks in the fabrication of functional molecules and show great potentials in the areas of supramolecular chemistry, smart materials, interface chemistry, and drug delivery, due to their advantages in structure and performance like rigid chiral backbone, multiple reactive sites, unique self-assembly ability, good biocompatibility and bioactivity. Glycyrrhetinic acid (GA) and glycyrrhizic acid (GL), two of the classic pentacyclic triterpenes, have attracted considerable attention in the synthesis of organic functional molecules in the past decade. In this paper, we focus on the recent progress of glycyrrhetinic acid/glycyrrhizic acid-derived small molecules and polymers, including design, synthesis, and applications in hydrogels, organogels, hybrid gels, chiral materials, thermo-and self-healable materials, agricultural Pickering-emulsions and polypseudorotaxanes.
- Natural triterpene,
- Glycyrrhizic acid,
- Glycyrrhetinic acid,
- Self-assembly,
- Host-guest interactions
1. [1]
  Qiu C, Wang J P, Qin Y, et al. J. Agric. Food Chem., 2019, 67:391~398.
2. [2]
  Wan Z L, Sun Y E, Ma L L, et al. Langmuir, 2018, 34:3971~3980.
3. [3]
  Gao Y X, Hao J, Liu J G, et al. Mater. Chem. Front., 2019, 3:308~313.
4. [4]
  Xiang M, Zhou X, Luo T R, et al. J. Agric. Food Chem., 2019, 67:13212~13220.
5. [5]
  Zou L W, Li Y G, Wang P, et al. Eur. J. Med. Chem., 2016, 112:208~288.
6. [6]
  Saha A, Adamcik J, Bolisetty S, et al. Angew. Chem. Int. Ed., 2015, 54:5408~5412.
7. [7]
  Kim A V, Shelepova E A, Selyutina O Y, et al. Mol. Pharm., 2019, 16:3188~3198.
8. [8]
  Cun X L, Chen J T, Li M M, et al. ACS Appl. Mater. Interf., 2019, 11:39545~39559
9. [9]
  Sun J, Liu H Y, Lv C Z, et al. J. Agric. Food Chem., 2019, 67:9643~9651.
10. [10]
  Hu J, Wu J D, Wang Q, et al. Beil. J. Org. Chem., 2013, 9:2877~2885.
11. [11]
  Gao Y X, Li Y, Zhao X, et al. RSC Adv., 2015, 5:102097~102100.
12. [12]
  Gao Y X, Hao J, Wu J D, et al. Nanoscale, 2015, 7:13568~13575.
13. [13]
  Gao Y X, Hao J, Wu J D, et al. Soft Matter, 2016, 12:8979~8982.
14. [14]
  Gao Y X, Hao J, Yan Q, et al. ACS Appl. Mater. Interf., 2018, 10:17352~17358.
15. [15]
  Ma Y, Gao Y X, Zhao X, et al. Chem. Eur. J., 2018, 24:11703~11710.
16. [16]
  Fang H S, Zhao X, Lin Y, et al. Chem. Asian J., 2018, 13:1192~1198.
17. [17]
  Li Y, Li J Z, Zhao X, et al. Chem. Eur. J., 2016, 22:18435~18441.
18. [18]
  Hao J, Gao Y X, Li Y, et al. Chem. Asian. J., 2017, 12:2231~2236.
19. [19]
  Xu G, Li J W, Wu J Q, et al. ACS Appl. Polym. Mater., 2019, 1:2577~2581.
20. [20]
  Hao J, Gao Y X, Zheng C H, et al. ACS Macro Lett., 2018, 7:1131~1137.
21. [21]
  Li Y, Gao Y X, Wang B, et al. Chem. Asian J., 2018, 13:2723~2729.
1. [1]
  Jin Tong , Shuyan Yu . Crystal Engineering for Supramolecular Chirality. University Chemistry, 2024, 39(3): 86-93. doi: 10.3866/PKU.DXHX202308113
2. [2]
  Ruoxi Sun , Yiqian Xu , Shaoru Rong , Chunmiao Han , Hui Xu . The Enchanting Collision of Light and Time Magic: Exploring the Footprints of Long Afterglow Lifetime. University Chemistry, 2024, 39(5): 90-97. doi: 10.3866/PKU.DXHX202310001
3. [3]
  Renjie Xue , Chao Ma , Jing He , Xuechao Li , Yanning Tang , Lifeng Chi , Haiming Zhang . Catassembly in the Host-Guest Recognition of 2D Metastable Self-Assembled Networks. Acta Physico-Chimica Sinica, 2024, 40(9): 2309011-0. doi: 10.3866/PKU.WHXB202309011
4. [4]
  Xiaofei NIU , Ke WANG , Fengyan SONG , Shuyan YU . Self-assembly of [Pd₆(L)₄]⁸⁺-type macrocyclic complexes for fluorescent sensing of HSO₃^-. Chinese Journal of Inorganic Chemistry, 2024, 40(7): 1233-1242. doi: 10.11862/CJIC.20240057
5. [5]
  Shihui Shi , Haoyu Li , Shaojie Han , Yifan Yao , Siqi Liu . Regioselectively Synthesis of Halogenated Arenes via Self-Assembly and Synergistic Catalysis Strategy. University Chemistry, 2024, 39(5): 336-344. doi: 10.3866/PKU.DXHX202312002
6. [6]
  Wenjian Zhang , Mengxin Fan , Wenwen Fei , Wei Bai . Cultivation of Critical Thinking Ability: Based on RAFT Polymerization-Induced Self-Assembly. University Chemistry, 2025, 40(4): 108-112. doi: 10.12461/PKU.DXHX202406099
7. [7]
  Wenjie SHI , Fan LU , Mengwei CHEN , Jin WANG , Yingfeng HAN . Synthesis and host-guest properties of imidazolium-functionalized zirconium metal-organic cage. Chinese Journal of Inorganic Chemistry, 2025, 41(1): 105-113. doi: 10.11862/CJIC.20240360
8. [8]
  Jinghua Wang , Yanxin Yu , Yanbiao Ren , Yesheng Wang . Integration of Science and Education: Investigation of Tributyl Citrate Synthesis under the Promotion of Hydrate Molten Salts for Research and Innovation Training. University Chemistry, 2024, 39(11): 232-240. doi: 10.3866/PKU.DXHX202402057
9. [9]
  Xinyu ZENG , Guhua TANG , Jianming OUYANG . Inhibitory effect of Desmodium styracifolium polysaccharides with different content of carboxyl groups on the growth, aggregation and cell adhesion of calcium oxalate crystals. Chinese Journal of Inorganic Chemistry, 2024, 40(8): 1563-1576. doi: 10.11862/CJIC.20230374
10. [10]
  Yingying Chen , Di Xu , Congmin Wang . Exploration and Practice of the “Four-Level, Three-Linkage” General Chemistry Course System. University Chemistry, 2024, 39(8): 119-125. doi: 10.3866/PKU.DXHX202401057
11. [11]
  Changqing MIAO , Fengjiao CHEN , Wenyu LI , Shujie WEI , Yuqing YAO , Keyi WANG , Ni WANG , Xiaoyan XIN , Ming FANG . Crystal structures, DNA action, and antibacterial activities of three tetranuclear lanthanide-based complexes. Chinese Journal of Inorganic Chemistry, 2024, 40(12): 2455-2465. doi: 10.11862/CJIC.20240192
12. [12]
  Ruiying WANG , Hui WANG , Fenglan CHAI , Zhinan ZUO , Benlai WU . Three-dimensional homochiral Eu(Ⅲ) coordination polymer and its amino acid configuration recognition. Chinese Journal of Inorganic Chemistry, 2025, 41(5): 877-884. doi: 10.11862/CJIC.20250052
13. [13]
  Xue Wu , Yupeng Liu , Bingzhe Wang , Lingyun Li , Zhenjian Li , Qingcheng Wang , Quansheng Cheng , Guichuan Xing , Songnan Qu . Rationally assembling different surface functionalized carbon dots for enhanced near-infrared tumor photothermal therapy. Acta Physico-Chimica Sinica, 2025, 41(9): 100109-0. doi: 10.1016/j.actphy.2025.100109
14. [14]
  Zihan Lin , Wanzhen Lin , Fa-Jie Chen . Electrochemical Modifications of Native Peptides. University Chemistry, 2025, 40(3): 318-327. doi: 10.12461/PKU.DXHX202406089
15. [15]
  Peng XU , Shasha WANG , Nannan CHEN , Ao WANG , Dongmei YU . Preparation of three-layer magnetic composite Fe₃O₄@polyacrylic acid@ZiF-8 for efficient removal of malachite green in water. Chinese Journal of Inorganic Chemistry, 2024, 40(3): 544-554. doi: 10.11862/CJIC.20230239
16. [16]
  Fengqiao Bi , Jun Wang , Dongmei Yang . Specialized Experimental Design for Chemistry Majors in the Context of “Dual Carbon”: Taking the Assembly and Performance Evaluation of Zinc-Air Fuel Batteries as an Example. University Chemistry, 2024, 39(4): 198-205. doi: 10.3866/PKU.DXHX202311069
17. [17]
  Rui Yang , Hui Li , Qingfei Meng , Wenjie Li , Jiliang Wu , Yongjin Fang , Chi Huang , Yuliang Cao . Influence of PC-based Electrolyte on High-Rate Performance in Li/CrO_x Primary Battery. Acta Physico-Chimica Sinica, 2024, 40(9): 2308053-0. doi: 10.3866/PKU.WHXB202308053
18. [18]
  Fengmiao Yu , Yang Sheng , Chanyue Li , Bao Li . The Three Lives of Aspirin. University Chemistry, 2024, 39(9): 115-121. doi: 10.12461/PKU.DXHX202402033
19. [19]
  Qingying Gao , Tao Luo , Jianyuan Su , Chaofan Yu , Jiazhu Li , Bingfei Yan , Wenzuo Li , Zhen Zhang , Yi Liu . Refinement and Expansion of the Classic Cinnamic Acid Synthesis Experiment. University Chemistry, 2024, 39(5): 243-250. doi: 10.3866/PKU.DXHX202311074
20. [20]
  Lanjun Cheng , Xinyuan Wang , Jie An , Xiang Wu , Chengfeng Zhu , Yanming Fu , Yougui Li . Improvement of the Resolution Experiment of Racemic Tartaric Acid. University Chemistry, 2025, 40(7): 277-285. doi: 10.12461/PKU.DXHX202408010

Get Citation

PDF

XML

Metrics

PDF Downloads(39)
Abstract views(2384)
HTML views(853)

通讯作者: 陈斌, bchen63@163.com

1.
沈阳化工大学材料科学与工程学院沈阳 110142