Citation: Zhang Jingshu, Tian Lei. Progress in Single Molecule Electrochemistry Based on Redox Recycling Signal Amplification[J]. Chemistry, ;2017, 80(12): 1104-1109. shu

Progress in Single Molecule Electrochemistry Based on Redox Recycling Signal Amplification

Zhang Jingshu ¹ ,
Tian Lei ^2,,

1.
College of Pharmacy, Xi'an Medical University, Xi'an 710021
2.
College of Chemistry & Materials Science, Northwest University, Xi'an 710127

Corresponding author: Tian Lei, tianl@nwu.edu.cn
Received Date: 23 June 2017
Accepted Date: 25 August 2017

Figures(5)

The development of modern analytical science has set a higher requirement for the sensitivity, selectivity and response speed of analytical methods. The detection and control of target molecules at the single molecule level is a challenging field that chemists have long dreamed of, and also a frontier for the development of analytical science in recent years. One of the challenges for direct analysis of single molecule by electrochemical methods is that the current caused by electron exchange of a single molecule during the redox process is too small to be detected by modern instruments. The direct electrochemical single-molecule analysis can be achieved through current amplification from massive repeat of electron exchange process on the electrode surface during redox reaction. This review summarized and compared the recent techniques and equipments for direct detection of single molecule electrochemically through amplification cycle. The future direction of development of single molecule electrochemistry was prospected too.
- Single molecule analysis,
- Electrochemistry,
- Redox recycling,
- Signal amplification
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沈阳化工大学材料科学与工程学院沈阳 110142