Citation: Kun ZOU, Jun WU, Chuang LIU, Zhi Hui XIAO. A Furostanol Saponin from the Cytotoxic Fraction of Tupistra chinensis Rhizomes[J]. Chinese Chemical Letters, ;2006, 17(10): 1335-1338. shu

A Furostanol Saponin from the Cytotoxic Fraction of Tupistra chinensis Rhizomes

Kun ZOU ^1, ,
Jun WU ² ,
Chuang LIU ¹ ,
Zhi Hui XIAO ²

1.
Hubei Key Laboratory of Natural Products Research and Development, College of Chemistry and Life Sciences, China Three Gorges University, Yichang 443002;
2.
Guangdong Key Laboratory of Marine Materia Medica, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou 510301

Received Date: 9 May 2006

Fund Project: This work was financially supported by the Scientific and Technological Foundation of China Three Gorges University (No. 2005ZD007).

A furostanol saponin was obtained from the n-butanol fraction of methanol extract from Tupistra chinensis rhizomes, a folk medicine of Shennongjia Forest District of Hubei Province.Its structure was determined as 3-O-β-D-glucopyranosyl-(25S)-22-O-methyl-5β-furost-1β, 3β, 5β,22α, 26-pentaol-26-O-β-D-glucopyranoside (1) on the basis of chemical and spectroscopic evidences. The n-butanol fraction displayed marked inhibitory activity in vitro towards HeLa and HL-60 human tumor cell lines by MTT method.
- Tupistra chinensis Bak.,
- furostanol saponin,
- cytotoxicity,
- folk medicines
1. [1]
  Jing JIN , Zhuming GUO , Zhiyin XIAO , Xiujuan JIANG , Yi HE , Xiaoming LIU . Tuning the stability and cytotoxicity of fac-[Fe(CO)₃I₃]^- anion by its counter ions: From aminiums to inorganic cations. Chinese Journal of Inorganic Chemistry, 2024, 40(5): 991-1004. doi: 10.11862/CJIC.20230458

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