Citation: Xian Hong YIN, Man Ya YANG, Hua Hong SHI, Lian Quan GU. Synthesis of 3 or 4-Substituted Pyridine-2, 6-Dicarboxylic Acid[J]. Chinese Chemical Letters, ;1999, 10(11): 903-906. shu

Synthesis of 3 or 4-Substituted Pyridine-2, 6-Dicarboxylic Acid

1.
Chemistry Department Zhongshan University Guangzhou 510275;
2.
Chemistry Department Guangxin University for Nationalities Nanning 530006

Received Date: 27 May 1999

Fund Project: We gratefully acknowledge support of this work by the National Natural Science Foundation of China (grant 29701006 to HHS) and the Natural Science Foundation of Guangdong Province (grant 960001 to HHS).

Various 4-alkoxypyridine-2, 6-dicarboxylic acids were synthesized starting from 2, 6 lutidine.Through aldol condensation and Michael addition, various 4-arylpyridine-2, 6 dicarboxylic acids were synthesized starting from aromatic aldehydes and 2-acetylfuran.
- Michael reaction,
- 2, 6-lutidine analogues,
- substituted pyridine-2, 6-dicarboxylic acids
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