Citation: Wang Guixia, Zhang Zhouyang, Liu Peng, Liao Peihai, Kong Xiangfei. Progress in the Syntheses of 4-Chromanone Derivatives with Bioactivities[J]. Chemistry, ;2017, 80(4): 322-328. shu

Progress in the Syntheses of 4-Chromanone Derivatives with Bioactivities

Guangxi Scientific Experiment Center of Mining, Metallurgy and Environment, College of Chemistry and Biological Engineering, Guilin University of Technology, Guilin 541004

Corresponding author: Kong Xiangfei, xiangfei.kong@glut.edu.cn
Received Date: 20 July 2016
Accepted Date: 15 November 2016

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4-Chromanone derivatives are widespread in nature, most of them have biological activities. 4-Chromanone derivatives with bioactivities are chiral compounds, especially C₂. The asymmetric synthesis of these compounds has attracted great attention. The key step of synthesizing of 4-chromanone derivatives is to control the synthesis of C₂ chiral center. In this paper, based on the different synthesis routes, various methods of synthesizing C₂ (racemic or chiral)-4-chromanone derivatives in recent years were summarized, and the reaction characteristics of synthesizing C₂ (chiral)-4-chromanone derivatives were discussed.
- 4-Chromanone derivatives,
- Bioactivity,
- Asymmetric synthesis,
- Cyclization
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