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Citation: Yu Xiang, Chen Yafang, Qin Yan, Yan Jing. Syntheses and Antifungal Activities of 5-Arylidene-2, 3-diaryl-thiazolidin-4-one Derivatives[J]. Chemistry, ;2019, 82(1): 68-73. shu

Syntheses and Antifungal Activities of 5-Arylidene-2, 3-diaryl-thiazolidin-4-one Derivatives

Yu Xiang ^1,2,, ,
Chen Yafang ¹ ,
Qin Yan ¹ ,
Yan Jing ¹

1.
College of Pharmacy, Guizhou University of Chinese Medicine, Guiyang 550025
2.
Guizhou Key Laboratory of Miao Medicine, Guizhou University of Chinese Medicine, Guiyang 550025

Corresponding author: Yu Xiang, yuxiangjx@126.com
Received Date: 28 July 2018
Accepted Date: 1 September 2018

Figures(1)

A series of 5-arylidene-2, 3-diaryl-thiazolidin-4-one derivatives (4a~4r) were synthesized from 2, 3-diphenyl-thiazolidin-4-one via microwave irradiation, and evaluated in vitro at the concentration of 100μg/mL against seven phytopathogenic fungi, namely Fusarium graminearum, Alternaria alternata, Fusarium oxysporium f. sp. vasinfectum, Pyricularia oryzae, Valsa mali, Alternaria solani and Alternaria brassicae. All the prepared compounds were characterized for structural confirmation by melting point, ¹H NMR, and MS. The activity results indicated that 4g and 4n exhibit potential antifungal activities against the phytopathogenic fungi.
- 5-Arylidene-2, 3-diary-lthiazolidin-4-one,
- Microwave irradiation,
- Antifungal activity
1. [1]
  R Ottana, R Maccari, M L Barreca et al. Bioorg. Med. Chem., 2005, 13: 4243~4252.
2. [2]
  D V Kamins'kyi, D V Khylyuk, R B Lesyk. Farm. Zhurnal-Kiev, 2010, 6: 36~43.
3. [3]
  A K Nag. Orient. J. Chem., 2012, 28(1): 541~545.
4. [4]
  A P Krishchishin, D V Kaminskii, N I Zelisko et al. Zh. Org. Farm. Khim., 2013, 11(2): 57~62.
5. [5]
  R Lakhan, R L Singh. J. Agric. Food Chem., 1991, 39(3): 580~583
6. [6]
  O Nuket, A Feray, T J Zuhal. Heterocycl. Chem., 2003, 40(4): 721~724.
7. [7]
  X Yu, Y F Chen. Chemstry (Huaxue Tongbao), 2018, 81(7): 657~659.
8. [8]
  X Yu, Y F Chen. Chemstry (Huaxue Tongbao), 2018, 81(8): 759~762.
1. [1]
  Yun-Feng Liu , Hui-Fang Du , Ya-Hui Zhang , Zhi-Qin Liu , Xiao-Qian Qi , Du-Qiang Luo , Fei Cao . Chaeglobol A, an unusual octocyclic sterol with antifungal activity from the marine-derived fungus Chaetomium globosum HBU-45. Chinese Chemical Letters, 2025, 36(3): 109858-. doi: 10.1016/j.cclet.2024.109858
2. [2]
  Qinwen Zheng , Xin Liu , Lintao Tian , Yi Zhou , Libing Liao , Guocheng Lv . Mechanism of Fenton catalytic degradation of Rhodamine B induced by microwave and Fe₃O₄. Chinese Chemical Letters, 2025, 36(4): 109771-. doi: 10.1016/j.cclet.2024.109771
3. [3]
  Tingting Liu , Pengfei Sun , Wei Zhao , Yingshuang Li , Lujun Cheng , Jiahai Fan , Xiaohui Bi , Xiaoping Dong . Magnesium doping to improve the light to heat conversion of OMS-2 for formaldehyde oxidation under visible light irradiation. Chinese Chemical Letters, 2024, 35(4): 108813-. doi: 10.1016/j.cclet.2023.108813
4. [4]
  Hailang Deng , Abebe Reda Woldu , Abdul Qayum , Zanling Huang , Weiwei Zhu , Xiang Peng , Paul K. Chu , Liangsheng Hu . Killing two birds with one stone: Enhancing the photoelectrochemical water splitting activity and stability of BiVO₄ by Fe ions association. Chinese Chemical Letters, 2024, 35(12): 109892-. doi: 10.1016/j.cclet.2024.109892
5. [5]
  Bing Xie , Qi Jiang , Fang Zhu , Yaoyao Lai , Yueming Zhao , Wei He , Pei Yang . Transdermal delivery of amphotericin B using deep eutectic solvents for antifungal therapy. Chinese Chemical Letters, 2025, 36(5): 110508-. doi: 10.1016/j.cclet.2024.110508
6. [6]
  Peipei CUI , Yawen ZHENG , Pan LI , Peiyan GUAN , Zhaohong QIAN . Praseodymium-organic framework with 4, 4′-oxybis(benzoic acid): Rare broken layer structure, antibacterial activity, and sensing for Cd²⁺ ions. Chinese Journal of Inorganic Chemistry, 2025, 41(8): 1641-1649. doi: 10.11862/CJIC.20250152
7. [7]
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8. [8]
  Anqiu LIU , Long LIN , Dezhi ZHANG , Junyu LEI , Kefeng WANG , Wei ZHANG , Junpeng ZHUANG , Haijun HAO . Synthesis, structures, and catalytic activity of aluminum and zinc complexes chelated by 2-((2,6-dimethylphenyl)amino)ethanolate. Chinese Journal of Inorganic Chemistry, 2024, 40(4): 791-798. doi: 10.11862/CJIC.20230424
9. [9]
  Qiang Cao , Xue-Feng Cheng , Jia Wang , Chang Zhou , Liu-Jun Yang , Guan Wang , Dong-Yun Chen , Jing-Hui He , Jian-Mei Lu . Graphene from microwave-initiated upcycling of waste polyethylene for electrocatalytic reduction of chloramphenicol. Chinese Chemical Letters, 2024, 35(4): 108759-. doi: 10.1016/j.cclet.2023.108759
10. [10]
  Hao Li , Hanzhi Lu , Linlin Hu , Xueli Zhang , Hua Shao , Fulun Li , Yanfei Shen . Dynamic surface-enhanced Raman spectroscopy-based metabolic profiling: A novel pathway to overcoming antifungal resistance. Chinese Chemical Letters, 2025, 36(7): 110342-. doi: 10.1016/j.cclet.2024.110342
11. [11]
  Chunwei Lei , Jian Li , Bo Xu , Yu Xie , Yun Ling , Juhua Luo , Wei Zhang . Synthesis of Ni/MnO/C nano-microspheres with synergistic effects of dielectric and magnetic loss for efficient microwave absorption. Chinese Chemical Letters, 2025, 36(7): 110419-. doi: 10.1016/j.cclet.2024.110419
12. [12]
  Bin Dong , Ning Yu , Qiu-Yue Wang , Jing-Ke Ren , Xin-Yu Zhang , Zhi-Jie Zhang , Ruo-Yao Fan , Da-Peng Liu , Yong-Ming Chai . Double active sites promoting hydrogen evolution activity and stability of CoRuOH/Co₂P by rapid hydrolysis. Chinese Chemical Letters, 2024, 35(7): 109221-. doi: 10.1016/j.cclet.2023.109221
13. [13]
  Jia Chen , Yun Liu , Zerong Long , Yan Li , Hongdeng Qiu . Colorimetric detection of α-glucosidase activity using Ni-CeO₂ nanorods and its application to potential natural inhibitor screening. Chinese Chemical Letters, 2024, 35(9): 109463-. doi: 10.1016/j.cclet.2023.109463
14. [14]
  Sanmei Wang , Dengxin Yan , Wenhua Zhang , Liangbing Wang . Graphene-supported isolated platinum atoms and platinum dimers for CO₂ hydrogenation: Catalytic activity and selectivity variations. Chinese Chemical Letters, 2025, 36(4): 110611-. doi: 10.1016/j.cclet.2024.110611
15. [15]
  Cailiang Yue , Nan Sun , Yixing Qiu , Linlin Zhu , Zhiling Du , Fuqiang Liu . A direct Z-scheme 0D α-Fe₂O₃/TiO₂ heterojunction for enhanced photo-Fenton activity with low H₂O₂ consumption. Chinese Chemical Letters, 2024, 35(12): 109698-. doi: 10.1016/j.cclet.2024.109698
16. [16]
  Ruiying Liu , Li Zhao , Baishan Liu , Jiayuan Yu , Yujie Wang , Wanqiang Yu , Di Xin , Chaoqiong Fang , Xuchuan Jiang , Riming Hu , Hong Liu , Weijia Zhou . Modulating pollutant adsorption and peroxymonosulfate activation sites on Co3O4@N,O doped-carbon shell for boosting catalytic degradation activity. Chinese Journal of Structural Chemistry, 2024, 43(8): 100332-100332. doi: 10.1016/j.cjsc.2024.100332
17. [17]
  Yan-Kai Zhang , Yong-Zheng Zhang , Chun-Xiao Jia , Fang Wang , Xiuling Zhang , Yuhang Wu , Zhongmin Liu , Hui Hu , Da-Shuai Zhang , Longlong Geng , Jing Xu , Hongliang Huang . A stable Zn-MOF with anthracene-based linker for Cr(VI) photocatalytic reduction under sunlight irradiation. Chinese Chemical Letters, 2024, 35(12): 109756-. doi: 10.1016/j.cclet.2024.109756
18. [18]
  Qian Wu , Mengda Xu , Tianjiao Ma , Shuzhen Yan , Jin Li , Xuesong Jiang . Chalcone-derived oxime esters with efficient photoinitiation properties under LED irradiation. Chinese Chemical Letters, 2025, 36(3): 110427-. doi: 10.1016/j.cclet.2024.110427
19. [19]
  Simin Wei , Yaqing Yang , Junjie Li , Jialin Wang , Jinlu Tang , Ningning Wang , Zhaohui Li . The Mn/Yb/Er triple-doped CeO₂ nanozyme with enhanced oxidase-like activity for highly sensitive ratiometric detection of nitrite. Chinese Chemical Letters, 2024, 35(6): 109114-. doi: 10.1016/j.cclet.2023.109114
20. [20]
  Peng Zhang , Yitao Yang , Tian Qin , Xueqiu Wu , Yuechang Wei , Jing Xiong , Xi Liu , Yu Wang , Zhen Zhao , Jinqing Jiao , Liwei Chen . Interface engineering of Pt/CeO₂-{100} catalysts for enhancing catalytic activity in auto-exhaust carbon particles oxidation. Chinese Chemical Letters, 2025, 36(2): 110396-. doi: 10.1016/j.cclet.2024.110396

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