Citation: Liu Qinghua, Yang Ping, Gao Chuanzhu, Yang Bo, Qian Yunxu. Research Progress in Gold Nanoparticle-Based Delivery Systems of Antitumor Platinum Drugs[J]. Chemistry, ;2017, 80(11): 995-1001. shu

Research Progress in Gold Nanoparticle-Based Delivery Systems of Antitumor Platinum Drugs

Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming 650500

Corresponding author: Gao Chuanzhu, gczasd@163.com
Received Date: 12 April 2017
Accepted Date: 13 July 2017

Figures(9)

Platinum drugs have become one of the most widely used anticancer drugs due to their unique mechanisms of action. However, the clinical use of platinum anticancer drugs were limited by serious side effects, drug resistance and other issues. In order to overcome the deficiencies of platinum anticancer drugs, improve the bioavailability of platinum anticancer drugs and reduce their side effects, targeted drug delivery system to change the in vivo transmission method of the platinum drugs has been widely concerned. Among of them, the platinum drugs-gold nanoparticles delivery system has significantly caused the attention of researchers for its high loading capacity, easy modification, cancer cells EPR effect and non-immunogenicity, etc. In this paper, the research progress in nanogold delivery systems for platinum-based antitumor drugs in recent ten years were introduced.
- Platinum drugs,
- Gold nanoparticles,
- Drug loading system
1. [1]
  P Ma, H Xiao, C Li et al. Mater. Today, 2015, 18(10): 554~564.
2. [2]
  H S Oberoi, N V Nukolova, A V Kabanov et al. Adv. Drug Deliv. Rev., 2013, 65(13-14): 1667~1685.
3. [3]
  P M Tiwari, K Vig, V A Dennis et al. Nanomaterials, 2011, 1(1): 31~63.
4. [4]
  D G I Kingston, J P Snyder. Acc. Chem. Res., 2014, 47(8): 2682~2691.
5. [5]
  Y Ding, Y Y Zhou, H Chen et al. Biomaterials, 2013, 34(38): 10217~10227.
6. [6]
  H R Zheng, L M Xu, Z L Zhang et al. Sci. Chin. Phys. Mech., 2010, 53(10): 1799~1804.
7. [7]
  N Bertrand, J Wu, X Xu et al. Adv. Drug Deliv. Rev., 2014, 66(24): 2~25.
8. [8]
  B Rosenberg, L Vancamp, J E Trosko et al. Nature, 1969, 222(5191): 385~386.
9. [9]
  H Wang, Y Yin, P Wang et al. Apoptosis, 2016, 21(7): 778~794.
10. [10]
  S Dilruba, G V Kalayda. Cancer Chemother. Pharmacol., 2016, 77(6): 1103~1124.
11. [11]
  P M Takahara, C A Frederick, S J Lippard. J. Am. Chem. Soc., 2014, 118(49): 12309~12321.
12. [12]
  X Wang, Z Guo. Chem. Soc. Rev., 2013, 42(1): 202~224.
13. [13]
  T C Johnstone, G Y Park, S J Lippard. Anticancer Res., 2014, 34(1): 471~476.
14. [14]
15. [15]
  L Xu, H Kuang, C Xu et al. J. Am. Chem. Soc., 2012, 134(3): 1699~1709.
16. [16]
  G Frens. Nature, 1973, 241(105): 20~22.
17. [17]
  C Yu, L Zhu, R Zhang et al. J. Phy. Chem. C, 2014, 118(19): 10434~10440.
18. [18]
  X Ma, Y Wu, S Jin et al. ACS Nano, 2015, 5(11): 8629~8639.
19. [19]
  M G Lewis, S Dafonseca, N Chomont et al. Aids, 2011, 25(11): 1347~1356.
20. [20]
  I Fratoddi, I Venditti, C Cametti et al. Nano Res., 2015, 8(6): 1771~1799.
21. [21]
  C Carnovale, G Bryant, R Shukla et al. Prog. Mater. Sci., 2016, 83: 152~190.
22. [22]
  R Caomilán, L M Lizmarzán. Expert Opin. Drug Del., 2014, 11(5): 741~752.
23. [23]
  A M Alkilany, S E Lohse, C J Murphy. Acc. Chem. Res., 2013, 46(3): 650~661.
24. [24]
25. [25]
  S Acharya, S K Sahoo. Adv. Drug Deliv. Rev., 2011, 63(3): 170~183.
26. [26]
  B Asadishad, M Vossoughi, I Alemzadeh. Ind. Eng. Chem. Res., 2010, 49(4): 1958~1963.
27. [27]
  X Kang, D Yang, Y Dai et al. Nanoscale, 2013, 5(1): 253~261.
28. [28]
  S Parveen, R Misra, SK Sahoo. Nanomed. Nanotechnol., 2012, 8(2): 147~166.
29. [29]
  S D Brown, P Nativo, J A Smith et al. J. Am. Chem. Soc., 2010, 132(13): 4678~4684.
30. [30]
  H Daraee, A Eatemadi, E Abbasi et al. Artif. Cell Blood Sub., 2016, 44(1): 1~13.
31. [31]
  S Salatin, S M Dizaj, A Y Khosroushahi. Cell Biol. Int., 2015, 39(8): 881~890.
32. [32]
  S Sau, P Agarwalla, S Mukherjee et al. Nanoscale. 2014, 6(12): 6745~6754.
33. [33]
  S Huo, S Jin, X Ma et al. ACS Nano, 2014, 8(6): 5852~5862.
34. [34]
  A J Wagstaff, S D Brown, M R Holden et al. Inorg. Chim. Acta, 2012, 393(12): 328~333.
35. [35]
  C Grandclement, C Borg. Cancers, 2011, 3(2): 1899~1928.
36. [36]
  A Ediriwickrema, W M Saltzman. ACS Biomater. Sci. Eng., 2015, 1(2): 64~78.
37. [37]
  C A Simpson, K J Salleng, D E Cliffel et al. Nanomed. Nanotechnol., 2013, 9(2): 257~263.
38. [38]
  A Kumar, S Huo, X Zhang et al. ACS Nano, 2014, 8(5): 4205~4220.
39. [39]
  T Wei, J Liu, H Ma et al. Nano Lett., 2013, 13(6): 2528~2534.
40. [40]
  A P Pandey, N M Girase, M D Patil et al. J. Nanosci. Nanotechnol., 2014, 14(1): 828~840.
41. [41]
  M Frenette, M Hatamimoslehabadi M, S Bellingerbuckley et al. J. Am. Chem. Soc., 2014, 136(45): 15853~15856.
42. [42]
  S Centi, F Tatini, F Ratto et al. J. Nanobiotech., 2014, 12(1): 55.
43. [43]
  Y Min, C Mao, D Xu et al. Chem. Commun., 2010, 46(44): 8424~8426.
44. [44]
45. [45]
  G D Moon, S W Choi, X Cai et al. J. Am. Chem. Soc., 2011, 133(13): 4762~4765.
46. [46]
  L Raguin, T Samrowski, C Hafner et al. Int. Soc. Opt. Photon., 2010, 7712(5): 77~89.
1. [1]
  Xiaoxuan Yu , Wukun Liu . Practice of Ideological and Political Education in Medicinal Chemistry for Pharmacy Administration Major: A Case Study on the Discovery of Cisplatin’s Anticancer Function. University Chemistry, 2025, 40(4): 408-414. doi: 10.12461/PKU.DXHX202405200
2. [2]
  Hong LI , Xiaoying DING , Cihang LIU , Jinghan ZHANG , Yanying RAO . Detection of iron and copper ions based on gold nanorod etching colorimetry. Chinese Journal of Inorganic Chemistry, 2024, 40(5): 953-962. doi: 10.11862/CJIC.20230370
3. [3]
  Ruiqin Feng , Ye Fan , Yun Fang , Yongmei Xia . Strategy for Regulating Surface Protrusion of Gold Nanoflowers and Their Surface-Enhanced Raman Scattering. Acta Physico-Chimica Sinica, 2024, 40(4): 2304020-0. doi: 10.3866/PKU.WHXB202304020
4. [4]
  Hongpeng He , Mengmeng Zhang , Mengjiao Hao , Wei Du , Haibing Xia . Synthesis of Different Aspect-Ratios of Fixed Width Gold Nanorods. Acta Physico-Chimica Sinica, 2024, 40(5): 2304043-0. doi: 10.3866/PKU.WHXB202304043
5. [5]
  Yuhao SUN , Qingzhe DONG , Lei ZHAO , Xiaodan JIANG , Hailing GUO , Xianglong MENG , Yongmei GUO . Synthesis and antibacterial properties of silver-loaded sod-based zeolite. Chinese Journal of Inorganic Chemistry, 2024, 40(4): 761-770. doi: 10.11862/CJIC.20230169
6. [6]
  Wenjun Yang , Qiaoling Tan , Wenjiao Xie , Xiaoyu Pan , Youyong Yuan . Construction and Characterization of Calcium Alginate Microparticle Drug Delivery System: A Novel Design and Teaching Practice in Polymer Experiments. University Chemistry, 2025, 40(3): 371-380. doi: 10.12461/PKU.DXHX202405150
7. [7]
  Yu Dai , Xueting Sun , Haoyu Wu , Naizhu Li , Guoe Cheng , Xiaojin Zhang , Fan Xia . Determination of the Michaelis Constant for Gold Nanozyme-Catalyzed Decomposition of Hydrogen Peroxide. University Chemistry, 2025, 40(5): 351-356. doi: 10.12461/PKU.DXHX202407052
8. [8]
  Chunmei GUO , Weihan YIN , Jingyi SHI , Jianhang ZHAO , Ying CHEN , Quli FAN . Facile construction and peroxidase-like activity of single-atom platinum nanozyme. Chinese Journal of Inorganic Chemistry, 2024, 40(9): 1633-1639. doi: 10.11862/CJIC.20240162
9. [9]
  Lina Liu , Xiaolan Wei , Jianqiang Hu . Exploration of Subject-Oriented Undergraduate Comprehensive Chemistry Experimental Teaching Based on the “STS Concept”: Taking the Experiment of Gold Nanoparticles as an Example. University Chemistry, 2024, 39(10): 337-343. doi: 10.12461/PKU.DXHX202405112
10. [10]
  Shiyang He , Dandan Chu , Zhixin Pang , Yuhang Du , Jiayi Wang , Yuhong Chen , Yumeng Su , Jianhua Qin , Xiangrong Pan , Zhan Zhou , Jingguo Li , Lufang Ma , Chaoliang Tan . Pt Single-Atom-Functionalized 2D Al-TCPP MOF Nanosheets for Enhanced Photodynamic Antimicrobial Therapy. Acta Physico-Chimica Sinica, 2025, 41(5): 100046-0. doi: 10.1016/j.actphy.2025.100046
11. [11]
  Jingke LIU , Jia CHEN , Yingchao HAN . Nano hydroxyapatite stable suspension system: Preparation and cobalt adsorption performance. Chinese Journal of Inorganic Chemistry, 2024, 40(9): 1763-1774. doi: 10.11862/CJIC.20240060
12. [12]
  Yanting HUANG , Hua XIANG , Mei PAN . Construction and application of multi-component systems based on luminous copper nanoclusters. Chinese Journal of Inorganic Chemistry, 2024, 40(11): 2075-2090. doi: 10.11862/CJIC.20240196
13. [13]
  Hongling Liu , Yue Xia , Guang Xu , Yafei Yang , Chunhua Qu . Bitter Cold Medicine, Good for Healing. University Chemistry, 2025, 40(3): 328-332. doi: 10.12461/PKU.DXHX202405039
14. [14]
  Xiuya Ma , Yu Chen , Yan Zhang . Stories about Pharmaceuticals. University Chemistry, 2025, 40(7): 232-240. doi: 10.12461/PKU.DXHX202408003
15. [15]
  Ziheng Zhuang , Xiao Xu , Kin Shing Chan . Superdrugs for Superbugs. University Chemistry, 2024, 39(9): 128-133. doi: 10.3866/PKU.DXHX202309040
16. [16]
  Zian Fang , Qianqian Wen , Yidi Wang , Hongxia Ouyang , Qi Wang , Qiuping Li . The Test Paper for Metal Ion: A Popular Science Experiment Based on Color Aesthetics. University Chemistry, 2024, 39(5): 108-115. doi: 10.3866/PKU.DXHX202310032
17. [17]
  Yuxia Luo , Xiaoyu Xie , Fangfang Chen . 药物递送魔法师——分子印迹聚合物. University Chemistry, 2025, 40(8): 202-210. doi: 10.12461/PKU.DXHX202409129
18. [18]
  Jiangjuan Shao , Xuan Li , Jingdan Weng , Xiaolei Chen , Fei Xu , Yulu Ma , Nianguang Li , Shizhong Zheng . Improvement in the Experimental Teaching Design of Physical and Chemical Identification and Quantification of Mineral Drugs. University Chemistry, 2024, 39(10): 137-142. doi: 10.3866/PKU.DXHX202312079
19. [19]
  Fa Wang , Yu Chen , Hui Chao . Ruthenium(II) Complexes as Photoactivated Chemo-Prodrugs for Hypoxic Tumor Therapy. University Chemistry, 2025, 40(7): 200-212. doi: 10.12461/PKU.DXHX202410024
20. [20]
  Hong RAO , Yang HU , Yicong MA , Chunxin LÜ , Wei ZHONG , Lihua DU . Synthesis and in vitro anticancer activity of phenanthroline-functionalized nitrogen heterocyclic carbene homo- and heterobimetallic silver/gold complexes. Chinese Journal of Inorganic Chemistry, 2024, 40(12): 2429-2437. doi: 10.11862/CJIC.20240275

Get Citation

PDF

XML

Metrics

PDF Downloads(69)
Abstract views(7360)
HTML views(1984)

通讯作者: 陈斌, bchen63@163.com

1.
沈阳化工大学材料科学与工程学院沈阳 110142