Citation: Wei Guo LI, Chao QI, Li DU, Zi LIU, Da Qing ZHAO, Jia Zuan NI. Preparation of Europium Induced Conformation-specific anti-calmodulin Monoclonal Antibody[J]. Chinese Chemical Letters, ;2002, 13(3): 215-216. shu

Preparation of Europium Induced Conformation-specific anti-calmodulin Monoclonal Antibody

Wei Guo LI ^1, ,
Chao QI ^1,2 ,
Li DU ² ,
Zi LIU ² ,
Da Qing ZHAO ¹ ,
Jia Zuan NI ¹

1.
Laboratory of Rare Earth Chemistry and Physics, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022;
2.
Department of Biochemistry, Quartermaster University of PLA, Changchun 130062

Received Date: 14 June 2001

Fund Project: This work is financially supported by the NNSF (No.29890280).

Monoclonal antibody technique was employed to detect the conformational difference of CaM induced by metal ions. A trivalent europium ion induced conformation-specific anti-calmodulin monoclonal antibody was successfully prepared with europium-saturated calmodulin as antigen.
- Calmodulin,
- europium,
- monoclonal antibody
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