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Citation: Wang Dongfang, Fu Xinbo, Zhao Yanan, Li Yang, Gao Wentao. Study on Syntheses of Halo-Functionalized 6-Hydrogen (hydrocarbyl)-6H-Indolo[2, 3-b]quinoxaline[J]. Chemistry, ;2017, 80(1): 69-76. shu

Study on Syntheses of Halo-Functionalized 6-Hydrogen (hydrocarbyl)-6H-Indolo[2, 3-b]quinoxaline

Institute of Superfine Chemicals, Bohai University, Jinzhou 121000

Corresponding author: Gao Wentao, isfc@bhu.edu.cn
Received Date: 20 May 2016
Accepted Date: 15 August 2016

Figures(2)

5-Halogenated isatins (1a~1d) were first N-alkylated to give the corresponding 1-alkyl-5-halogenated isatins (2a~2t). Subsequently, 1a~1d and 2a~2t were condensated with o-diaminobenzene in acetic acid to afford a series of 6H-indolo[2, 3-b]quinoxaline derivatives (3a~3x) with yields of 65%~88%. Among them, ten compounds were unreported in the literatures and their structures were confirmed by IR, ¹H NMR, ¹³C NMR spectra and HRMS.
- 6H-indolo[2, 3-b]quinoxaline,
- Halo-functionalized,
- Alkylation,
- Halogenated isatin,
- o-Diaminobenzene
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