Citation: Xue Pengxian, Long Zerong, Yuan Hui, Lan Wei. Research Advances in the Quality and Toxicology of Sulfur-Fumigated Chinese Medicine Materials[J]. Chemistry, ;2019, 82(7): 598-605, 597. shu

Research Advances in the Quality and Toxicology of Sulfur-Fumigated Chinese Medicine Materials

Xue Pengxian ^1,2 ,
Long Zerong ^2,, ,
Yuan Hui ² ,
Lan Wei ^1,,

1.
School of Chinese Pharmacy, Xingjing Medical University, Urumqi 83000
2.
Xinjing Uygur Autonomous Region Product Quality Supervision and Inspection Institute, Urumqi 830011

Corresponding author: Long Zerong, long8326rong@163.com Lan Wei, lanwei516@sina.com
Received Date: 14 March 2019
Accepted Date: 20 April 2019

Figures(13)

Sulfur fumigation is a traditional drying method to prevent Chinese medicine materials from insects, molds and erosion etc, and can be used to bleach them. In recent years, investigations have found that the certain active components of traditional Chinese medicine (TCM) can be transformed into sulfur-containing derivatives in the process of sulfur fumigation, resulting in changes of metabolism and pharmacodynamics in the body, and even production of toxic reactions. This paper comprehensively summarizes the various morphologies of sulfur elements, chemical transformation rules of TCM and the toxicological studies in sulfur-fumigation. The review would provide valuable references for further evaluating the rationality of sulfur fumigation process of TCM.
- Sulfur fumigation,
- Chinese herbal medicine,
- Morphology of sulfur element,
- Sulfur-containing derivatives,
- Toxicology
1. [1]
2. [2]
  X Jiang, L P Huang, S H Zheng et al. J. Sci. Food. Agric., 2013, 93: 2963-2972.
3. [3]
4. [4]
  K Pei, H Cai, X Liu et al. J. Sep. Sci., 2015, 38(1): 25-33.
5. [5]
6. [6]
7. [7]
8. [8]
9. [9]
  J Liu, H Cai, X Liu et al. J. Chin. Med., 2011, 36(13): 1790-1793.
10. [10]
  H Zhang, J Chen, H Xiong et al. Org. Biomol. Chem., 2019, 17(06): 1-6.
11. [11]
  F K Tittel, H Wu, H Zheng et al. Optics Express, 2017, 25(26): 32581-32590.
12. [12]
13. [13]
14. [14]
15. [15]
16. [16]
  G Viviana, S Alida, C C Victor et al. Antioxidants, 2018, 7(7): 87-104.
17. [17]
  D L Tang, Q Wang, Y N Chu et al. Spectrosc. Spect. Anal., 2018, 38(4): 1319-1323.
18. [18]
  D H Truong, M A Eghbal, W Hindmarsh et al. Drug. MeTab. Rev., 2006, 38(4): 733-744.
19. [19]
20. [20]
  L Dan, H Duan, Y Ma et al. Anal. Chem., 2018, 90(09): 5719-5727.
21. [21]
22. [22]
  X X Cui, H H Yi, X L Tang et al. J. Chem. Technol. Biotechnol., 2018, 93(3): 720-729.
23. [23]
  V N Rad, M Anbia, M H Sadr. J. Environ. Sci-China., 2018, 15(3): 631-636.
24. [24]
25. [25]
  Z W Jia, B P Mao, S Miao et al. Acta Pharm. Sin., 2014, 49(2): 277-281.
26. [26]
27. [27]
28. [28]
29. [29]
  S Senthilkumaran, R G Menezes, S M M Ibrahim. Am. J. Emerg. Med., 2014, 32(1): 86-89.
30. [30]
31. [31]
  L Xiao, T Jiang, J Nie et al. J. Chin. Med., 2016, 41(12): 2216-2220.
32. [32]
  C Wang, C Liang, J Ma et al. J. Biochem. Mol. Toxic., 2017, 32(02): 1-5.
33. [33]
  M J Abramson, G P Benke, J Cui et al. Occup. Environ. Med., 2010, 67(10): 679-685.
34. [34]
  X B Wang, H F Jin, C S Tang et al. Clin. Exp. Pharmacol. Physiol., 2010, 37(7): 745-752.
35. [35]
36. [36]
37. [37]
38. [38]
39. [39]
  J D Xu, Q Mao, H Shen et al. J. Chromatogr. A., 2013, 13(4): 154-168.
40. [40]
41. [41]
  S L Li, S Hong, L Y Zhu et al. J. Chromatogr. A., 2012, 31(12): 31-45.
42. [42]
  B Ma, W L Kan, H Zhu et al. J. Ethnopharmcol., 2017, 195: 222-230.
43. [43]
  A L Guo, L M Chen, Y M Wang et al. Molecules, 2014, 19(10): 16640-16655.
44. [44]
45. [45]
  X Q Ma, A K Leung, C L Chan et al. Analyst, 2014, 139(2): 505-516.
46. [46]
  P Y Hayes, R Lehmann, K Penman et al. Tetrahed. Lett., 2005, 46(15): 2615-2618.
47. [47]
  S L Li, J Z Song, F F Choi et al. J. Pharm. Biomed. Anal., 2009, 49(2): 253-266.
48. [48]
  M Kong, H H Liu, J Xu et al. J. Pharm. Biomed. Anal., 2014, 98(10): 424-433.
49. [49]
  M Kong, H H Liu, J Wu et al. J. Ethnopharmacol., 2018, 212: 95-105.
50. [50]
51. [51]
  X Y Li, J D Xu, J Xu et al. Anal. Methods-UK., 2016, 8(5): 1034-1043.
52. [52]
  Y J Bai, J D Xu, M Kong et al. Food. Res. Int., 2015, 76: 387-394.
53. [53]
  Y X Zhan, P Yao, W C Bi et al. Phytomedicine, 2014, 21(11): 1318-1324.
54. [54]
  H Cai, G Cao, L Li et al. Molecules, 2013, 18(2): 1368-1382.
55. [55]
  Z Y Li, H M Gao, J Sun et al. Helv. Chim. Acta., 2012, 95(7): 1144-1151.
56. [56]
57. [57]
  J B S Braveman. J. Sci. Food. Agric., 2010, 4(11): 540-547.
58. [58]
59. [59]
60. [60]
61. [61]
  X H Wang, P S Xie, C W Lam et al. J. Pharm. Biomed. Anal., 2009, 49(5): 1221-1225.
62. [62]
63. [63]
64. [64]
  S Wang, L J Hao, J J Zhu et al. Phytomedicine, 2014, 21(5): 773-779.
65. [65]
  X Y Xing, Z H Sun, M H Yang et al. Molecules, 2018, 23(10): 2609.
66. [66]
  C Z Kang, Z Dan, L P Kang et al. Front. Plant. Sci., 2018, (1): 790-802.
67. [67]
  X Q Ma, S M Li, T Su et al. Chin. Med-UK, 2016, 11(1): 32-44.
68. [68]
69. [69]
  K Ding, G Cao, Z Xu et al. Nat. Prod. Commun., 2014, 9(9): 1357-1358.
70. [70]
  J W Zhao, C Y Zheng, H Wei et al. Chem-Biol. Interact., 2018, 292: 84-93.
71. [71]
  M H Yuan, Z G Yan, L Yuan et al. J. Ethnopharmacol., 2019, 234: 76-84.
72. [72]
73. [73]
  B Duan, L Huang, S Chen. Phytomedicine, 2012, 19(6): 562-568.
74. [74]
75. [75]
  J He, Y He, C Zhang. Molecules, 2017, 22(9): 1402.
76. [76]
  Z L Zhan, A P Deng, L P Kang et al. J. Pharm. Biomed. Anal., 2018, 156: 340-348.
77. [77]
  L He, Z Zhang, Y Liu et al. Food. Res. Int., 2018, 108: 226-236.
78. [78]
  L Zhang, H Shen, J Xu et al. Food. Chem., 2017, 246: 202-210.
79. [79]
  D Liu, F Galvanin, Y Yu. AAPS. PharmSciTech., 2018, 19(2): 1-10.
80. [80]
  M H Mirjalili, P Salehi, M M Vala et al. Ind. J. Plant. Physiol., 2019, (4): 1-8.
1. [1]
  Tao Wang , Qin Dong , Cunpu Li , Zidong Wei . Sulfur Cathode Electrocatalysis in Lithium-Sulfur Batteries: A Comprehensive Understanding. Acta Physico-Chimica Sinica, 2024, 40(2): 2303061-0. doi: 10.3866/PKU.WHXB202303061
2. [2]
  Weihan Zhang , Menglu Wang , Ankang Jia , Wei Deng , Shuxing Bai . Surface Sulfur Species Influence Hydrogenation Performance of Palladium-Sulfur Nanosheets. Acta Physico-Chimica Sinica, 2024, 40(11): 2309043-0. doi: 10.3866/PKU.WHXB202309043
3. [3]
  Yan'e LIU , Shengli JIA , Yifan JIANG , Qinghua ZHAO , Yi LI , Xinshu CHANG . MoO₃/cellulose derived carbon aerogel: Fabrication and performance as cathode for lithium-sulfur battery. Chinese Journal of Inorganic Chemistry, 2025, 41(8): 1565-1573. doi: 10.11862/CJIC.20250054
4. [4]
  Hongyao Li , Youyan Liu , Luwei Dai , Min Yang , Qihui Wang . The Blessing of Indium Sulfide：Confronting the Narrow Path with Uric Acid. University Chemistry, 2024, 39(5): 325-335. doi: 10.3866/PKU.DXHX202311104
5. [5]
  Hong CAI , Jiewen WU , Jingyun LI , Lixian CHEN , Siqi XIAO , Dan LI . Synthesis of a zinc-cobalt bimetallic adenine metal-organic framework for the recognition of sulfur-containing amino acids. Chinese Journal of Inorganic Chemistry, 2025, 41(1): 114-122. doi: 10.11862/CJIC.20240382
6. [6]
  Jinyao Du , Xingchao Zang , Ningning Xu , Yongjun Liu , Weisi Guo . Electrochemical Thiocyanation of 4-Bromoethylbenzene. University Chemistry, 2024, 39(6): 312-317. doi: 10.3866/PKU.DXHX202310039
7. [7]
  Nan Xiao , Fang Sun . 二芳基硫醚化合物的构建及应用. University Chemistry, 2025, 40(6): 360-363. doi: 10.12461/PKU.DXHX202407099
8. [8]
  Weikang Wang , Yadong Wu , Jianjun Zhang , Kai Meng , Jinhe Li , Lele Wang , Qinqin Liu . Green H₂O₂ synthesis via melamine-foam supported S-scheme Cd_0.5Zn_0.5In₂S₄/S-doped carbon nitride heterojunction: synergistic interfacial charge transfer and local photothermal effect. Acta Physico-Chimica Sinica, 2025, 41(8): 100093-0. doi: 10.1016/j.actphy.2025.100093
9. [9]
  Jianfeng Yan , Yating Xiao , Xin Zuo , Caixia Lin , Yaofeng Yuan . Comprehensive Chemistry Experimental Design of Ferrocenylphenyl Derivatives. University Chemistry, 2024, 39(4): 329-337. doi: 10.3866/PKU.DXHX202310005
10. [10]
  Yiming Liang , Ziyan Pan , Kin Shing Chan . One Drink, Two Tears in the Central Nervous System: The Perils of Disulfiram-Like Reactions. University Chemistry, 2025, 40(4): 322-325. doi: 10.12461/PKU.DXHX202406016
11. [11]
  Xue Xiao , Jiachun Li , Xiangtong Meng , Jieshan Qiu . Sulfur-Doped Carbon-Coated Fe_0.95S_1.05 Nanospheres as Anodes for High-Performance Sodium Storage. Acta Physico-Chimica Sinica, 2024, 40(6): 2307006-0. doi: 10.3866/PKU.WHXB202307006
12. [12]
  Jia-He Li , Yu-Ze Liu , Jia-Hui Ma , Qing-Xiao Tong , Jian-Ji Zhong , Jing-Xin Jian . 洛芬碱衍生物的合成、化学发光与重金属离子检测. University Chemistry, 2025, 40(6): 230-237. doi: 10.12461/PKU.DXHX202407080
13. [13]
  Qianli Ma , Tianbing Song , Tianle He , Xirong Zhang , Huanming Xiong . Sulfur-doped carbon dots: a novel bifunctional electrolyte additive for high-performance aqueous zinc-ion batteries. Acta Physico-Chimica Sinica, 2025, 41(9): 100106-0. doi: 10.1016/j.actphy.2025.100106
14. [14]
  Ruiqing LIU , Wenxiu LIU , Kun XIE , Yiran LIU , Hui CHENG , Xiaoyu WANG , Chenxu TIAN , Xiujing LIN , Xiaomiao FENG . Three-dimensional porous titanium nitride as a highly efficient sulfur host. Chinese Journal of Inorganic Chemistry, 2024, 40(5): 867-876. doi: 10.11862/CJIC.20230441
15. [15]
  Haitao Wang , Lianglang Yu , Jizhou Jiang , Arramel , Jing Zou . S-Doping of the N-Sites of g-C₃N₄ to Enhance Photocatalytic H₂ Evolution Activity. Acta Physico-Chimica Sinica, 2024, 40(5): 2305047-0. doi: 10.3866/PKU.WHXB202305047
16. [16]
  Zhongyan Cao , Shengnan Jin , Yuxia Wang , Yiyi Chen , Xianqiang Kong , Yuanqing Xu . Advances in Highly Selective Reactions Involving Phenol Derivatives as Aryl Radical Precursors. University Chemistry, 2025, 40(4): 245-252. doi: 10.12461/PKU.DXHX202405186
17. [17]
  Xiaofei Liu , He Wang , Li Tao , Weimin Ren , Xiaobing Lu , Wenzhen Zhang . Electrocarboxylation of Benzylic Phosphates and Phosphinates with Carbon Dioxide. Acta Physico-Chimica Sinica, 2024, 40(9): 2307008-0. doi: 10.3866/PKU.WHXB202307008
18. [18]
  Yingtong Shi , Guotong Xu , Guizeng Liang , Di Lan , Siyuan Zhang , Yanru Wang , Daohao Li , Guanglei Wu . PEG-VN改性PP隔膜用于高稳定性高效率锂硫电池. Acta Physico-Chimica Sinica, 2025, 41(7): 100082-0. doi: 10.1016/j.actphy.2025.100082
19. [19]
  Yonghui ZHOU , Rujun HUANG , Dongchao YAO , Aiwei ZHANG , Yuhang SUN , Zhujun CHEN , Baisong ZHU , Youxuan ZHENG . Synthesis and photoelectric properties of fluorescence materials with electron donor-acceptor structures based on quinoxaline and pyridinopyrazine, carbazole, and diphenylamine derivatives. Chinese Journal of Inorganic Chemistry, 2024, 40(4): 701-712. doi: 10.11862/CJIC.20230373
20. [20]
  Yikai Wang , Xiaolin Jiang , Haoming Song , Nan Wei , Yifan Wang , Xinjun Xu , Cuihong Li , Hao Lu , Yahui Liu , Zhishan Bo . Thickness-Insensitive, Cyano-Modified Perylene Diimide Derivative as a Cathode Interlayer Material for High-Efficiency Organic Solar Cells. Acta Physico-Chimica Sinica, 2025, 41(3): 2406007-0. doi: 10.3866/PKU.WHXB202406007

Get Citation

PDF

XML

Metrics

PDF Downloads(20)
Abstract views(1114)
HTML views(356)

通讯作者: 陈斌, bchen63@163.com

1.
沈阳化工大学材料科学与工程学院沈阳 110142