Citation: DENG Xiao-Yan, PENG Hao, HE Hong-Wu. Synthesis, Characterization and X-ray Crystal Structure of 4-Fluoro-N-(2-methyl-5-((2-(p-tolyloxy)acetamido)-methyl)pyrimidin-4-yl)benzamide[J]. Chinese Journal of Structural Chemistry, ;2014, 33(2): 223-227. shu

Synthesis, Characterization and X-ray Crystal Structure of 4-Fluoro-N-(2-methyl-5-((2-(p-tolyloxy)acetamido)-methyl)pyrimidin-4-yl)benzamide

1.
Key Laboratory of Pesticide and Chemical Biology, Ministry of Education, and College of Chemistry, Central China Normal University, Wuhan 430079, China

Corresponding author: PENG Hao,
Received Date: 19 June 2013
Available Online: 5 December 2013
Fund Project: This work was supported by the National Basic Research Program of China (2010CB126100) (2010CB126100)

A new crystal of 4-fluoro-N-(2-methyl-5-((2-(p-tolyloxy)acetamido)methyl)pyrimidin-4-yl)benzamide has been prepared at room temperature and characterized by ¹H NMR, ¹³C-NMR, IR, MS, elemental analysis and X-ray single-crystal determination. The compound crystallizes in monoclinic, space group P2₁/c with a=17.226(5), b=13.934(4), c=17.262(5) Å,β=92.180(5)°, V=4140(2) Å³, D_c=1.311 g/cm³, Z=8, F(000)=1712 and μ=0.095 mm^-1. The molecular packing in the crystal is the result of N-H…O hydrogen bonds.
- X-ray crystallography,
- acetamido,
- benzamide,
- pyrimidin
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