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Citation: Hu Yunhua, Zhuo Renxi. Preparation of Long-Chain Fatty Acid Esters of Cellulose in LiCl/DMAc System and Their Drug Release Properties[J]. Chinese Journal of Applied Chemistry, ;1996, 13(2): 7-10. shu

Preparation of Long-Chain Fatty Acid Esters of Cellulose in LiCl/DMAc System and Their Drug Release Properties

Hu Yunhua ,
Zhuo Renxi

1.
Department of Chemistry, Wuhan University, Wuhan 430072

Received Date: 9 June 1995
Available Online: 27 December 1995
Fund Project:

Long-chain fatty acid esters of cellulose were prepared by the reaction of cellulose with acid chlorides in LiCl/DMAc solution.The effects of reaction conditions on the degree of substitution were studied.The results showed that the degree of substitution could reach 2.85 under proper reaction conditions. The drug release properties from these cellulose ester matrixes were also investigated.
- cellulose,
- esterification,
- LiCl/DMAc,
- controlled drug release
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