Citation:
Zhu Chuanfang, Xiao Haiyan, Li Zhonghua. Studies on Synthesis of Nitriloalkylenephosphonic Acids(Ⅳ):Synthesis of N-Alkyl-α-Aminobenzylenephosphonic Acids in Tetramethylenesulfone[J]. Chinese Journal of Applied Chemistry,
;1997, 14(3): 107-108.
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Some N-alkyl-T-aminobenzylenephosphonic acids were prepared directly from benzaldehyde or p-nitrobenzaldehyde with amines and phosphorous acid using tetramethylenesulfone as solvent. The method offers the advantages of giving good yields, easy purification of the products, simplicity and rapidity.
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