Citation: Wu Xiaoyun, Yin Xiaogang, Gong Wei, Chen Zhiming, Chen Zhuo. Syntheses of 2-Amino-3-cyano-4H-pyran Derivatives Catalyzed by Zinc Acetate[J]. Chemistry, ;2016, 79(12): 1156-1160. shu

Syntheses of 2-Amino-3-cyano-4H-pyran Derivatives Catalyzed by Zinc Acetate

1.
Key Laboratory of Functional Materials Chemistry of Guizhou Province, School of Chemistry and Materials Science, Guizhou Normal University, Guiyang 550001

Corresponding author: Chen Zhuo,
Received Date: 22 May 2016
Available Online: 15 August 2016
Fund Project:

2-Amino-4H-pyran derivatives were synthesized under the catalysis of zinc acetate using cyano chalcones and malononitrile as raw materials. Influences of catalysts, solvents, reaction time and temperature, mole ratio of raw material on the yield were studied. The optimal conditions are as follows, molar ratio of cyano chalcones and malononitrile is 1:1, zinc acetate (10(mol)%) as catalyst, methylene chloride as solvent, the reaction temperature is 30℃. Under this condition, the highest yield of target product can reach 99.5%.
- Zinc acetate,
- Tandem reaction,
- 2-Amino-3-cyano-4H-pyran derivatives
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沈阳化工大学材料科学与工程学院沈阳 110142