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Citation: Wang Zhicai, Lin Dianwei, Zheng Qihuang. SYNTHESIS OF ADENINE DERIVATIVES BY SOLID-LIQUID PHASE TRANSFER CATALYSIS[J]. Chinese Journal of Applied Chemistry, ;1993, 10(3): 42-46. shu

SYNTHESIS OF ADENINE DERIVATIVES BY SOLID-LIQUID PHASE TRANSFER CATALYSIS

1.
Department of Chemistry, Zhongshan University, 510275 Guangzhou

Received Date: 14 July 1992
Available Online: 8 December 1992

Adenine derivatives as pharmaceuticals-eritadenine (1), ethyl 4-(6-amino-9H-purine-9-yl)-2(R), 3(R)-dihydroxybutyrate (1_a),β-adenylpropionic acid (2) and ethyl β-adenylpropionate (2_a) have been synthesized by solid-liquid phase transfer eatalysis. The effects of reaction conditions on the yields were studied. The results showed that PEG is a good phase transfer catalyst for the reaction.
- adenine derivative,
- solid-liquid phase transfer catalysis,
- synthesis
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