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Citation: Gao Bi, Wang Zhicai, Zheng Qihuang, Xu Zhiwen. STUDIES ON SYNTHESIS OF A/B RING ANALOGUES OF CASTASTERONE Ⅱ. STEREOSELECTIVE SYNTHESIS OF 2β,3β-DIHYDROXY-6-CHOLESTERONE[J]. Chinese Journal of Applied Chemistry, ;1993, 10(1): 12-15. shu

STUDIES ON SYNTHESIS OF A/B RING ANALOGUES OF CASTASTERONE Ⅱ. STEREOSELECTIVE SYNTHESIS OF 2β,3β-DIHYDROXY-6-CHOLESTERONE

1.
1. Department of Chemistry, Zhongshan University, 510275 Guangzhou;
2.
2. Department of Chemistry, Xiamen University, Xiamen

Received Date: 3 March 1992
Available Online: 24 June 1992

2β, 3β-Dihydroxy-6-cholesterone, a structural analogue in A/B rings of castasterone was stereoselectively synthesized from cholesterol via nitration, reduction; elimination and oxidation reactions. The key step in the synthesis is the introduction of 2β, 3β-dihydroxy groups by oxidation with I₂-AgOAe-H₂O.
- 2β,3β-dihydroxycholesterone,
- castasterone,
- A/B ring analogue,
- I₂-AgOAc oxidation,
- synthesis
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