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Citation: MA Zhong-Hua, CHEN Qiong. Synthesis and Biological Activities of Triazolopyrimidine Thiomethylene Triazolothio-Ether Derivatives[J]. Chinese Journal of Applied Chemistry, ;2009, 26(8): 885-889. shu

Synthesis and Biological Activities of Triazolopyrimidine Thiomethylene Triazolothio-Ether Derivatives

MA Zhong-Hua ^a,b ,
CHEN Qiong ^b,,

1.
a College of Basic Sciences, Huazhong Agricultural University, Wuhan;
2.
b College of Chemistry, Central China Normal University, Wuhan 430079

Corresponding author: CHEN Qiong,
Received Date: 20 July 2008
Available Online: 20 November 2008
Fund Project: 国家自然科学基金(20702018)资助项目 (20702018)

Ten novel diheterocyclic thio-ether compounds containing 1,2,4-triazolo[1,5-a] pyrimidine and 1,2,4-triazole moieties were designed and synthesized with 2-mercapto-5,7-dimethyl-[1,2,4]triazolo[I,5-a] pyrimidine as starting material.All the compounds obtained were comfired by MS and ¹H NMR.Preliminary biological activity test indicates most of compounds 6 display good activity against C.beticola.Especially,compounds 6b,6e,6f,6g and 6h can reach grade A(≥90%) at a concentration of 50 μg/L.
- triazolopyrimidine,
- triazolothio-ether,
- synthesis,
- biological activity
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