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Citation: DING Rong-Chang, DONG Wen-Ju, FENG Jiu-Ju. Cyclic Voltammetry Determination of Uric Acid at a L-Phenylalanine Modified Electrode[J]. Chinese Journal of Applied Chemistry, ;2009, 26(7): 822-825. shu

Cyclic Voltammetry Determination of Uric Acid at a L-Phenylalanine Modified Electrode

1.
College of Chemistry and Environmental Science, Key Laboratory of Environmental Science and Engineering, Education Commision of Henan Province, Henan Normal University, Xinxiang 453007

Corresponding author: DONG Wen-Ju,
Received Date: 16 July 2008
Available Online: 18 September 2008
Fund Project: 河南省自然科学基金(2000150034) (2000150034)

L-Phenylalanine modified electrode was prapared and used to detect uric acid(UA) in urine via cyclic voltammetry.In phosphate buffer solution(pH=5.6),UA displayed a sensitive oxidation peak at 0.43 V on L-phenylalanine modified electrode.The peak current was well proportional to the concentration of UA in a range of 2.0×10^-6~3.0×10^-4 mol/L with a detection limit of 1×10^-6 mol/L.The relative standard deviation was estimated to be 3.0% from the parallel determinations of 1.0×10^-5 mol/L uric acid in quintuplicate.The modified electrode is easy to prepare with good reproducibility and has been applied to the determination of UA in urine with satisfactory results.
- L-phenylalanine,
- modified electrode,
- uric acid,
- cyclic voltammetry
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