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Citation: Yang Zhengyin, Wang Liufang, Wu Jigui, Li Xingyu. SYNTHESIS,CHARACTERIZATION AND ANTITUMOR ACTIVITY OF COMPLEXES OF 2-CARBONYLPROPIONYL (PYRIDINE-4-FORMYL) HYDRAZONE WITH RARE EARTHS[J]. Chinese Journal of Applied Chemistry, ;1992, 9(3): 31-36. shu

SYNTHESIS,CHARACTERIZATION AND ANTITUMOR ACTIVITY OF COMPLEXES OF 2-CARBONYLPROPIONYL (PYRIDINE-4-FORMYL) HYDRAZONE WITH RARE EARTHS

1.
Department of Chemistry, Lanzhou University, Lanzhou 73000

Corresponding author: Wang Liufang,
Received Date: 9 March 1991
Available Online: 20 August 1991
Fund Project:

2-Carbonylpropionyl (pyridine-4-formyl) hydrazone (H₂PPPH) has been synthesized by a simple method. It is a weak acid, and the complexation was carried out in the water solution of rare earth carbonates. 13 complexes have general composition of RE₂(PPFH)₃·nH₂O (RE=La~Yb, n=2~3). The structures and properties of the complexes were characterized by elemental analysis, IR, UV spectra, TGA-DTA, molar conductance and ¹H NMR measuramcnts. Eu₂(PPFH)₃·3H₂O was showed to have a certain antitumor activity.
- 2-carbonylpropionic acid,
- isonicotinyl hydrazine,
- hydrazone,
- rare earth
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