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Citation: Li Zengmin, Hu Bingfang. THE MECHANISM OF ANTIBACTERIAL ACTIVITY OF 2-AMINO-1,2,3-THIADIAZOLE IN CONTROLLING LEAF BLIGHT OF RICE[J]. Chinese Journal of Applied Chemistry, ;1988, 5(4): 54-57. shu

THE MECHANISM OF ANTIBACTERIAL ACTIVITY OF 2-AMINO-1,2,3-THIADIAZOLE IN CONTROLLING LEAF BLIGHT OF RICE

Li Zengmin ,
Hu Bingfang

1.
Institute of Applied Chemistry, Beijing Agricultural University

Received Date: 4 November 1987
Available Online: 4 January 1988

The synthesis of 11 novel compounds of 5-substituted 2-amino-l,3,4-thiadiazole and 2-substituted amino-l,3,4-thiadiazoles are described.The bactericidal activity against Xanthomonas campestris pv oryzae in vivo of about 30 ATDA analogues is observed.2-Amino-5-car-boxyl-l,3,4-thiadiazole exhibites an excellent bactericidal activity.It is postulated that the acive compound which can serve as the competitor of nicotinamide in metabolite.system in bacteria cell seems to be 2-amino-5-carboxyl-l,3,4-thiadiazole rather than ATDA itself.
- 2-Amino-1,3,4-thiadiazole compounds,
- Antibacterial activity,
- Leaf blight of rice Synthesis,
- Structure-property relation
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