Citation: Yan Changling, Zhang Chunduo, Fan Hongzhe, Chen Yujuan, Li Jin, Liu Xun, Wang Gongke. Molecularly Imprinted Electrochemical Sensor for Ciprofloxacin hydrochloride[J]. Chemistry, ;2016, 79(1): 66-70. shu

Molecularly Imprinted Electrochemical Sensor for Ciprofloxacin hydrochloride

1.
1. School of Chemistry and Chemical Engineering, Henan Normal University, Xinxiang 453007;
2.
2. The Third affiliated Hospital of Xinxiang Medical University, Xinxiang 453000

Received Date: 9 March 2015
Available Online: 29 July 2015
Fund Project:

Molecular imprinting technique was used to prepare electrochemical sensor for ciprofloxacin hydrochloride (CPX) by electrochemical polymerization on the surface of graphite electrode using pyrrole as functional monomer. The effect of preparation conditions on sensor was investigated and the performances of the sensor were measured by square wave voltammetry (SWV) with ferricyanide as an electrochemical probe. The results showed that the peak current was linear to the negative logarithm of CPX concentration in the range from 1.0×10^-8 to 1.0×10^-4 mol/L with a detection limits (S/N=3) of 3.5×10^-9 mol/L. The sensor has good selectivity, reproducibility and stability for template CPX and the peak current of the sensor did not clearly change after stored for 15 days.
- Molecular imprinting,
- Ciprofloxacin hydrochloride,
- Pyrrole,
- Electrochemical sensors
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沈阳化工大学材料科学与工程学院沈阳 110142