Citation:
LI Wan-Hu, LU Jun, Ma Huai-Rang. Synthesis of 3,4-Dihydropyrimidin-2(1H)-ones Using Lanthanum Chloride as a Catalyst[J]. Chinese Journal of Applied Chemistry,
;2001, 18(7): 566-568.
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An efficient one-pot synthesis method for 3,4-dihydropyrimidinones using lanthanum chloride heptahydrate as a catalyst by the reaction of aldehyde, U-keto ester and urea(in molar ratio 1:1:1.5) in ethanol is described.The method is simple and affords product in good yield(80%~90%).
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