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Citation: CHEN Wen-Bin, JIN Gui-Yu. Syntheses and Biological Activities of α-[(1H-1,2,4-Triazol-1-yl)methyl]-β-aryl-β-arylthio-β-aryl-β-arylthio Substituted Phenylpropanol[J]. Chinese Journal of Applied Chemistry, ;2002, 19(6): 527-530. shu

Syntheses and Biological Activities of α-[(1H-1,2,4-Triazol-1-yl)methyl]-β-aryl-β-arylthio-β-aryl-β-arylthio Substituted Phenylpropanol

CHEN Wen-Bin ,
JIN Gui-Yu ^,

1.
State Key Laboratory of Elemento Organic Chemistry, Institute of Elemento Organic Chemistry, Nankai University, Tianjin 300071

Corresponding author: JIN Gui-Yu,
Received Date: 5 November 2001
Available Online: 21 February 2002
Fund Project: 国家自然科学基金资助项目(29832050) (29832050)

A series of the title compounds 5 were synthesized by reduction of compound 4 by using NaBH₄. The later were obtained by 1,4-nucleophilic addition of 1,3-diaryl-2-[(1H-1,2,4-triazol-1-yl)methyl]-2-propen-1-one 7 with substituted thiophenol. The structures of compounds 5 were characterized by elemental analysis, ¹H NMR and IR spectral measurements. Most of compounds 5 were found to have weak fungicidal activities against Puccinia recondita for wheat.
- triazole,
- synthesis,
- reduction,
- fungicidal activities
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