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Citation: CHE Chao, MAO Shu-Fen, QIN Zhao-Hai. Synthesis and Bioactivity of 2-Amino-5[(2-chloropyrid)-4-yl]-1,3,4-thiadiazole Derivatives[J]. Chinese Journal of Applied Chemistry, ;2002, 19(8): 795-797. shu

Synthesis and Bioactivity of 2-Amino-5[(2-chloropyrid)-4-yl]-1,3,4-thiadiazole Derivatives

1.
College of Applied Chemistry, China Agricultural University, Beijing 100094

Corresponding author: QIN Zhao-Hai,
Received Date: 26 November 2001
Available Online: 6 March 2002

By combining 2-chloropyridine, 1,3,4-thiadiazole and acylamide, three toxophoric moieties seven 2-[N-(1-methoxycarbonyl)ethyl-N-acyl]amino-5-[(2-chloropyrid)-4-yl]-1,3,4-thiadiazoles(8) were synthesized in seven steps. The preliminary biological activity tests show that the title compounds reveal a certain plant growth regulating effect as well as fungicidal activity.
- chloropyridine,
- thiadiazole,
- acylamide,
- synthesis,
- bioactivity
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