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Citation: XU Zhi-Feng, DING Ming-Wu. Synthesis and Biological Activity of Imidazoline Derivatives Containing Ferrocenyl Moity[J]. Chinese Journal of Applied Chemistry, ;2003, 20(2): 198-200. shu

Synthesis and Biological Activity of Imidazoline Derivatives Containing Ferrocenyl Moity

XU Zhi-Feng ^a,, ,
DING Ming-Wu ^b

1.
a Department of Chemistry, Hengyang Normal College, Hengyang 421008;
2.
b Institute of Organic Synthesis, Central China Normal University, Wuhan

Corresponding author: XU Zhi-Feng,
Received Date: 25 July 2002
Available Online: 22 October 2002
Fund Project: 湖南省普通高校青年骨干教师培养经费资助项目、衡阳师范学院科学基金启动项目(2000D04) (2000D04)

The easily accesible azidoethylacetate 1 was reacted with ferrocene formaldehyde to give azide 2, which was allowed to take Staudinger reactions with triphenylphosphine to give iminophosphorane 3. The imidazolinone derivatives containing ferrocenyl moity(5a~5e) were synthesized by a tandem aza-Wittig reaction of 3 with phenyl isocynate and substituted phenols in yields of 57%~69%. The structures of title compounds were confirmed by elemental analysis,IR and ¹H NMR. Two of them 5b and 5c exhibited fungicidal activities and none of them has herbicidal activity and insecticidal activity.
- imidazolinone,
- synthesis,
- aza-Wittig reaction,
- biological activity
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