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Citation: ZHU Feng, LIN Yong-Cheng, ZHOU Shi-Ning, L. L. P. VRIJMOED. Sterigmatocystin Isolated from Mangrove Endophytic Fungus No.2526[J]. Chinese Journal of Applied Chemistry, ;2003, 20(3): 272-274. shu

Sterigmatocystin Isolated from Mangrove Endophytic Fungus No.2526

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a School of Chemistry & Chemical Engineering, Zhongshan University, Guangzhou 510275;
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b School of Life Sciences, Zhongshan University, Guangzhou;
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c Department of Chemistry & Chemical Engineering, Foshan University, Foshan;
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d Department of Biology & Chemistry, City University of HongKong, HongKong

Corresponding author: LIN Yong-Cheng,
Received Date: 7 August 2002
Available Online: 4 November 2002
Fund Project: 国家863(2001AA624010) (2001AA624010)国家自然科学基金资助项目(20072058) (20072058)

Compound A was isolated from endophytic fungus (No.2526) of mangrove Avicennia from the South China Sea. The structure of compound A was elucidated by comprehensive spectral data and coincided with that of sterigmatocystin. Compound A showed a weak cytotoxic activity against Bel-7402 and NCIH-460 in vitro with IC₅₀ 96.53×10^-6 and 72.52×10^-6 g/mL respectively. It is the first report on sterigmatocystin that isolated from marine fungus.
- mangrove endophytic fungus,
- sterigmatocystin,
- cytotoxic activity
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