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Citation: HU Bing-Cheng, LÜ Chun-Xu, LIU Zu-Liang. Improvement on the Synthesis of 3-Methyl-4-carboethoxy-2-cyclohexen-1-one[J]. Chinese Journal of Applied Chemistry, ;2003, 20(10): 1012-1014. shu

Improvement on the Synthesis of 3-Methyl-4-carboethoxy-2-cyclohexen-1-one

1.
School of Chemical Engineering, Nanjing University of Science & Technology, Nanjing 210094

Corresponding author: HU Bing-Cheng,
Received Date: 24 January 2003
Available Online: 9 June 2003

The method for synthesis of the title compound has been improved, with product yield being increased to 58%. The following measures have been adopted:using 1,8-diazabicyclo[5.4.0]undec-7-ene(DBU) as catalyst instead of piperidine; adding benzene in the reaction mixture to favor azeotropic dehydration. The optimum molar ratio of DBU/ethylacetoacetate/solid paraformaldehyde was 4:20:11.
- methylcarboethoxycyclohexenone,
- diazabicycloundecene,
- paraformaldehyde,
- synthesis
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