Citation:
YIN Yu-Ji, YAO Kang-De, LIU Wen-Guang, MAO Jin-Shu, CUI Yuan-Lu, CAI Kai-Yong, ZHAO Feng. Chitosan-Gelatin Network Based Biomaterials in Tissue Engineering[J]. Chinese Journal of Applied Chemistry,
;2004, 21(3): 217-222.
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Chitosan in which the N-acetylglucosamine moiety is a structural feature found in glucosaminoglycans and gelatin is the partially denatured derivative of collagen. They exhibit related bioactivities as their precursor. The recent achievements on the chitosan-gelatin network based biomaterials are reviewed is this paper covers preparations of membrane, scaffold, surfaces modifier in tissue engineering as well as the utilization of N-alkylated chitosan as non-viral vector for DNA delivery. These biomaterials have promising perspectives in skin, cartilage, bone tissue engineering and gene therapy.
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Keywords:
- chitosan,
- gelatin,
- surface modification,
- biomaterial,
- tissue engineering,
- review
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