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Citation: YIN Yu-Ji, YAO Kang-De, LIU Wen-Guang, MAO Jin-Shu, CUI Yuan-Lu, CAI Kai-Yong, ZHAO Feng. Chitosan-Gelatin Network Based Biomaterials in Tissue Engineering[J]. Chinese Journal of Applied Chemistry, ;2004, 21(3): 217-222. shu

Chitosan-Gelatin Network Based Biomaterials in Tissue Engineering

1.
Research Institute of Polymeric Materials, Tianjin University, Tianjin 300072

Corresponding author: YAO Kang-De,
Received Date: 14 May 2003
Available Online: 16 December 2003
Fund Project: 国家重点基础规划项目(G199905305) (G199905305)国家自然科学基金(59973014、5983002、59883002、50233020、50203007) (59973014、5983002、59883002、50233020、50203007)

Chitosan in which the N-acetylglucosamine moiety is a structural feature found in glucosaminoglycans and gelatin is the partially denatured derivative of collagen. They exhibit related bioactivities as their precursor. The recent achievements on the chitosan-gelatin network based biomaterials are reviewed is this paper covers preparations of membrane, scaffold, surfaces modifier in tissue engineering as well as the utilization of N-alkylated chitosan as non-viral vector for DNA delivery. These biomaterials have promising perspectives in skin, cartilage, bone tissue engineering and gene therapy.
- chitosan,
- gelatin,
- surface modification,
- biomaterial,
- tissue engineering,
- review
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