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Citation: LIU Yan-Qin, HAN Shi-Tian, CHEN Su-Xia. Syntheses of Pyridylporphyrin-5-fluorouracil Compounds[J]. Chinese Journal of Applied Chemistry, ;2005, 22(2): 219-221. shu

Syntheses of Pyridylporphyrin-5-fluorouracil Compounds

1.
College of Chemistry, Hebei Normal University, Shijiazhuang 050091

Corresponding author: HAN Shi-Tian,
Received Date: 27 March 2004
Available Online: 22 July 2004
Fund Project: 河北省自然科学基金资助项目(203147) (203147)河北省教育厅资助项目(2001120) (2001120)

Three pyridylporphyrin-5-fluorouracil compounds, pyridylporphyrin quaternary ammonium bromide, were synthesized by the reaction of monopyridyl trisubstituted phenylporphyrins with 1-(3-bromo-propyl)-5-fluorouracil in refluxing dimethylformamide, and the yield was 32.1%~40.4%. The structures of the products were characterized by elemental analysis, UV-vis, IR, ¹H NMR and MS spectro-scopies.
- pyridylporphyrin,
- fluorouracil,
- synthesis
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