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Citation: ZHU Yan-Yun, CHEN Xi-Hui, HUANG Chu-Sheng, LIU Hong-Xing, LIN Xin-Long. Total Syntheses of Two Natural Benzopranylchalcones[J]. Chinese Journal of Applied Chemistry, ;2005, 22(5): 560-562. shu

Total Syntheses of Two Natural Benzopranylchalcones

1.
a College of Chemistry and Chemical Engineering, Guangxi University, Nanning 530004;
2.
b Department of Chemistry, Guangxi Teacher College, Nanning 530001

Corresponding author: HUANG Chu-Sheng,
Received Date: 16 September 2004
Available Online: 12 January 2005
Fund Project: 国家自然科学基金(20062001) (20062001)广西自然科学基金(0007016) (0007016)广西"新世纪十百千人才工程"资金(20012205)资助项目 (20012205)

A concise route for the total syntheses of benzopranylchalcones from 2,4,6-trihydroxyacetophone (3) and citral (8),by means of cyclization,methoxy-protection and aldol-condensation is described.Two benzopranylchalcones,Boesenbergin B(1) and Boesenbergin A(2) were synthesized from 2,4,6-(trihydroxyacetophone)(3),citral (8) and benzaldehyde (9) via the route.The total yields of compounds 1 and 2 were 26% and 11%,respectively.In the cyclization step,the yields of key intermediates 4 and 7 were 40% and 42%,respectively.
- total synthesis,
- Benzopranylchalcone,
- trihydroxyacetophone,
- citral,
- benzaldehyde
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