Citation:
WU Lin-Bo, ZHANG Jun-Chuan, JING Dian-Ying, DING Jian-Dong. A “Room-Temperature” Compression Molding Method for Fabrication of Poly (ε-caprolactone) Porous Scaffolds[J]. Chinese Journal of Applied Chemistry,
;2005, 22(9): 1024-1026.
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A novel room-temperature compression molding method combined with particulate leaching was developed to fabricate porous polyester scaffolds with the anatomical shape of the tissue or organ potentially applied in tissue engineering.Complicated-shaped scaffolds,such as auricle-like ones,were successfully fabricated from compression-molding putty-like mixture of concentrated poly(ε-caprolactone) solution and salt particulate in a mould with a complicated-shaped cavity at room temperature.The resultant porosity can reach over 90%.This room-temperature compression molding method is proven to be very convenient to fabricate three-dimensional porous scaffolds composed of biodegradable polymers.
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