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Citation: XU Huan-Zhi, YU Liang-Min, LI Chang-Cheng, ZHANG Zhi-Ming. Synthesis of Acrylamides Containing Capsaicin Derivative Moiety and Their Growth Inhibition Against Nitzschia Closterium[J]. Chinese Journal of Applied Chemistry, ;2007, 24(8): 911-916. shu

Synthesis of Acrylamides Containing Capsaicin Derivative Moiety and Their Growth Inhibition Against Nitzschia Closterium

1.
Key Laboratory of Marine Chemistry Theory and Technology of Ministry of Education, Qingdao Key LaboratoryFor Marine Fine Chemicals and Chemical Engineering, Ocean University of China, Qingdao 266003

Corresponding author: XU Huan-Zhi,
Received Date: 7 October 2006
Available Online: 30 March 2007
Fund Project: 国家高技术研究发展计划(2003AA322060、2001AA623030等) (2003AA322060、2001AA623030等)新世纪优秀人才支持计划(NCET-04-0644) (NCET-04-0644)

Nine uniquely functionalized antifouling acrylamide monomers derived from capsaicin were designed and synthesized.The yield of the reaction and the mp were respectively analyzed,and their stuctures were characterized by ¹H NMR and FTIR.Seven of them including BMA,TMBA,HMTBA,HMMBA,CHBA,BHBA,HDMBA were synthesized for the first time.Growth inhibition assay result in the laboratory shows that those synthesized monomers possess an antifouling activity against Nitzschia closterium in the order of HDMBA >DMBA≈BMA >TMBA≈HMTBA >CHBA >HMMBA >BHBA >HMBA.
- capsaicin,
- acrylamide,
- antifouling,
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