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Citation: SUN Ting, YANG Gui-Qiu, YU Xiu-Lan. Synthesis and Bioactivity of Novel Aryl Acrylates[J]. Chinese Journal of Applied Chemistry, ;2007, 24(10): 1193-1196. shu

Synthesis and Bioactivity of Novel Aryl Acrylates

SUN Ting ^a,, ,
YANG Gui-Qiu ^a,b ,
YU Xiu-Lan ^b

1.
a School of Sciences, Northeastern University, Shenyang 110004;
2.
b Department of Pharmaceutical Engineering, Shenyang Institute of Chemical Technology, Shenyang

Corresponding author: SUN Ting,
Received Date: 13 October 2006
Available Online: 20 January 2007

Five novel aryl acrylates were synthesized from Baylis-Hillman adducts according to the principle of combination of bioactive substructures. Their structures were confirmed by IR, ¹H NMR and elemental analysis. Preliminary bioactivities of these new compounds were evaluated in the green house. The result indicates that the target compounds have no insecticidal activity at 600 g a.i./hm² and no fungicidal activity at 400 g a.i./hm². The target compounds show certain herbicidal activity against Zinnia elegans Jacq., Abutilon theophrasti Medic., Echinochloa crusgalli(L.) Baeuv. and Digitaria sanguinalis (L.) Scop at 2 000 g a.i./hm². These compounds are brand new and contain versatile multifunctional molecules that could easily be modified and used as lead compounds for further study.
- (Hydroxy)methyl acrylate,
- aryl acrylate,
- bioactivity
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