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Citation: GONG Mei-Juan, LI Jing, HAN Tao, CAI Chen-Xin, LU Tian-Hong, GE Cun-Wang, DU Jiang-Yan. Evaluation of DNA-CNTs Modified Electrods by Electrochemical Methods[J]. Chinese Journal of Applied Chemistry, ;2008, 25(9): 1037-1041. shu

Evaluation of DNA-CNTs Modified Electrods by Electrochemical Methods

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a Department of Chemistry and Environmental Science, Nanjing Normal University, Nanjing 210097;
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b Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun;
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c School of Chemistry and Chemical Engineering, Nantong University, Nantong

Corresponding author: DU Jiang-Yan,
Received Date: 20 October 2007
Available Online: 29 February 2008
Fund Project: 江苏省普通高校自然科学研究计划(06KJB150054) (06KJB150054)江苏省自然科学基金(BK2005138) (BK2005138)分子医学生物技术江苏省重点实验室基金(MMBKF05001) (MMBKF05001)国家自然科学基金(60571055)资助项目 (60571055)

DNA modified carbon nanotubes electrodes are widely used in various fields and the immobilization step is of vital importance to them.Based on the carbon nanotubes(CNTs)-modified glassy carbon(GC)(CNTs/GC) electrode,two kinds of DNA-modified CNTs/GC(DNA-CNTs/GC) electrodes were fabricated by means of the absorption method and covalent bonding method.The electrochemical characteristics of the DNA-CNTs/GC electrodes were investigated via the cyclic voltammetry,differential pulse voltammetry and electrochemical impedance technique with Th as electrochemically active indicator.The results indicate that the DNA-CNTs/GC electrode prepared with the covalent bonding method possesses advantages of a large immobilization amount of DNA on the electrode surface and good stability,which could be used in the fields of electrochemical gene biosensors.
- DNA,
- carbon nanotube,
- modified electrode,
- thionine,
- electro-active indicator
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