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Citation: WEI Wen-Long, CAO Gui-Rong, CHANG Hong-Hong, LIU Qiang, WANG Zhi-Zhong. Synthesis of Chlorophenyl Isocyanates with Triphosgene[J]. Chinese Journal of Applied Chemistry, ;2008, 25(11): 1369-1371. shu

Synthesis of Chlorophenyl Isocyanates with Triphosgene

1.
College of Chemistry and Chemical Engineering, Taiyuan University of Technology, Taiyuan 030024

Corresponding author: WEI Wen-Long,
Received Date: 18 October 2007
Available Online: 11 January 2008
Fund Project: 太原市大学生创新资助项目(07010752) (07010752)

A new method to synthesize chlorophenyl isocyanates from corredponding chloroanilines and triphosgene was studied.The optimal reaction conditions were found via investigating the effects of solvent,reaction time and mole ratio of reactants on the yield.The results show that the optimal sovent is 1,2-dichlo-roethane,the optimal reaction time to prepare o-chlorophenyl isocyanates,m-chlorophenyl isocyanates and p-chlorophenyl isocyanates is respectively 5 h,4.5 h and 4.5 h,the optimal mole ratio of corredponding chloroanilines and triphosgene is respectively 2.2:1,2:1 and 2:1.Under those conditions,the highest yields of o-chlorophenyl isocyanates m-chlorophenyl isocyanates and p-chlorophenyl isocyanates are respectively 84.7%,86.2% and 89.0%,and the purities of the products are respectively 96.18%,97.83% and 99.55%.
- triphosgene,
- chloroanilines,
- chlorophenyl isocyanates,
- synthesize
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