Citation: Ting-Ting Li, Cui Xu, Chang-Bin Xiang, Jie Yan. An efficient chlorination of aromatic compounds using a catalytic amount of iodobenzene[J]. Chinese Chemical Letters, ;2013, 24(6): 535-538. shu

An efficient chlorination of aromatic compounds using a catalytic amount of iodobenzene

1.
a College of Chemical Engineering and Materials Sciences, Zhejiang University of Technology, Hangzhou 310032, China;
2.
b Foreign Language School, Zhejiang Shuren University, Hangzhou 310015, China

Corresponding author: Jie Yan,
Received Date: 6 January 2013
Available Online: 19 March 2013

An efficient method was developed for chlorination of aromatic compounds with electron-donating groups using iodobenzene as the catalyst and m-chloroperbenzoic acid as the terminal oxidant in the presence of 4-methylbenzenesulfonic acid in THF at room temperature for 24 h, and a series of the monochlorinated compounds was obtained in good yields. In this protocol, the catalyst iodobenzene was first oxidized into the hypervalent iodine intermediate, which then treated with lithium chloride and finally reacted with aromatic compounds to form the chlorinated compounds.
- Hypervalent iodine intermediate,
- Chlorination,
- Catalytic oxidation,
- Synthesis
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1.
沈阳化工大学材料科学与工程学院沈阳 110142