Citation: Li Minhao, Wang Zeming, Yang Jie, Wang Jiaxi. Advances in Monolithic Columns Technology in HPLC[J]. Chemistry, ;2019, 82(1): 18-26. shu

Advances in Monolithic Columns Technology in HPLC

School of Chemical Engineering and Technology, Hebei University of Technology, Tianjin 300130

Corresponding author: Wang Jiaxi, wangjiaxi@ebu.edu.cn
Received Date: 1 July 2018
Accepted Date: 25 September 2018

Figures(9)

As a new type of separating medium, high performance liquid chromatography (HPLC) monolithic columns have attracted considerable attention on account of its own characteristics, such as the simple preparation process, easy to be modified and excellent separation properties. Especially, due to its favorable biocompatibility, high column efficiency, long life, wide of the raw material source, good repeatability, unrestricted by pH, polymer-based monolithic columns are frequently used to separate and detect some small molecules compounds and proteins in food, chemical industry, agriculture, environment and biomedical science, which have shown a promising application prospect. Refer to the latest reports about HPLC, this review will focus on the research achievements of the preparation, modification method and application of monolithic columns in recent ten years. In addition, the future prospects for development regarding monolithic columns in various fields are also expected.
- HPLC,
- Stationary phase,
- Polymeric monolith
1. [1]
2. [2]
  H Wang, J Ou, J Bai et al. J. Chromatogr. A, 2016, 1436:100~108.
3. [3]
  D L Mould, R L M Synge. Analyst, 1958, 77(1952):964~970.
4. [4]
5. [5]
  C Aydogǧan, F Yılmaz, D Çimen et al. Electrophoresis, 2013, 34(13):1908~1914.
6. [6]
  D Gharbharan, D Britsch, G Soto et al. J. Chromatogr. A, 2015, 1408:101~107.
7. [7]
  K Cabrera, G Wieland, D Lubda et al. Trends Anal. Chem., 1998, 17(1):50~53.
8. [8]
  B Bidlingmaier, K K Unger, N V Doehren. J. Chromatogr. A, 1999, 832:11~16.
9. [9]
  Y F Shen, R Zhang, R J Moore et al. Anal. Chem., 2005, 77(10):3090~3100.
10. [10]
11. [11]
  N Itoh, T Santa, M Kato. Anal. Bioanal. Chem., 2015, 407(21):6429~6434.
12. [12]
13. [13]
  P Jandera, T Hajek, M Stankova. Anal. Bioanal. Chem., 2015, 407(1):139~151.
14. [14]
  M R Buchmeiser. Polymer, 2007, 48(8):2187~2198.
15. [15]
  D Fan, L Jia, H Xiang et al. Food Chem., 2017, 224:32~36.
16. [16]
  H Shao, L Zhao, J Chen et al. J. Pharm. Biomed. Anal., 2015, 111:241~247.
17. [17]
18. [18]
  S Aȿir, A Derazshamshir, F Yılmaz et al. Electrophoresis, 2015, 36(23):2888~2895.
19. [19]
20. [20]
  L X Chen, X Y Wang, W H Lu et al. J. Chem. Soc. Rev., 2016, 45(8):2137~2211.
21. [21]
22. [22]
  C Zheng, Y P Huang, Z S Liu. J. Sep. Sci., 2011, 34:1988~2002.
23. [23]
  G Y Sun, D D Zhong, X J Li et al. Anal. Bioanal. Chem., 2015, 407(24):7401~7412.
24. [24]
  J B Jiang, Q Zhou, C C Kang et al. J. Appl. Polym. Sci., 2013, 129(6):3425~3431.
25. [25]
  C Algieri, E Drioli, L Guzzo et al. Sensors, 2014, 14(8):13863~13912.
26. [26]
  H M Duan, X J Wang, Y H Wang et al. RSC Adv., 2015, 5(107):88492~88499.
27. [27]
  S A Zaidi. Biomater. Sci., 2017, 5(3):388~402.
28. [28]
  K Nakazato, J Mohammad, S Hjertén. Chromatographia, 1994, 39:655~662.
29. [29]
  M Chocholouskova, M Komendova, J Urban. J. Chromatogr. A, 2017, 1488:85~92.
30. [30]
  X Dong, R Wu, J Dong et al. Electrophoresis, 2008, 29(4):919~927.
31. [31]
  G Zhu, H Yuan, P Zhao et al. Electrophoresis, 2006, 27(18):3578~3583.
32. [32]
  F M Plieva, J Andersson, I Y Galaev et al. J. Sep. Sci., 2004, 27:828~836.
33. [33]
  F Svec, J M J Frechet. Science, 1996, 273:205~211.
34. [34]
35. [35]
  H Ren, X Zhang, Z Li et al. J. Sep. Sci., 2017, 40(4):826~833.
36. [36]
  F Svec. J. Chromatogr. A, 2010, 1217(6):902~924.
37. [37]
  R Guo, D Zhang, X Zhu et al. Chromatographia, 2016, 80(1):23~30.
38. [38]
  M Paljevac, J Kotek, K Jerǎbek et al. Macromol. Mater. Eng., 2018, 303(2):1700337~170344.
39. [39]
  J F Wang, X Y Jiang, H Zhang et al. Anal. Methods, 2015, 7(18):7879~7888.
40. [40]
  G Guiochon. J. Chromatogr. A, 2007, 1168:101~168.
41. [41]
  W J Han, Y R Xin, U Hasegawa et al. Polym. Degrad. STab., 2014, 109:362~366.
42. [42]
  P Simone, G Pierri, P Foglia et al. J. Sep. Sci., 2016, 39(2):264~271.
43. [43]
  S Currivan, J M Macak, P Jandera. J. Chromatogr. A, 2015, 1402:82~93.
44. [44]
  P Guo, Z Luo, X Xu et al. Food Chem., 2017, 217:628~636.
45. [45]
  T Hirano, S Kitagawa, H Ohtani et al. Anal. Bioanal. Chem., 2013, 405(25):8319~8326.
46. [46]
  D Grzywinski, M Szumski, B Buszewski. J. Chromatogr. A, 2016, 1477:11~21.
47. [47]
48. [48]
  T Koriyama, T A Asoh, A Kikuchi. Colloid. Surf., B, 2016, 147:408~415.
49. [49]
  Z Mao, Z Chen. J. Chromatogr. A, 2017, 1480:99~105.
50. [50]
  S Liu, J Peng, Z Liu et al. Sci. Rep., 2016, 6:34718~34728.
51. [51]
  Z Lin, H Huang, S Li et al. J. Chromatogr. A, 2013, 1271(1):115~123.
52. [52]
53. [53]
  A M James, D Hayes. Anal. Chem., 2000, 72(17):4090~4099.
54. [54]
  Z Zhang, Z Wu, M J Wirth. J. Chromatogr. A, 2013, 1301:156~161.
55. [55]
  R E Birdsall, B M Koshel, Y Hua et al. Electrophoresis, 2013, 34(5):753~760.
56. [56]
  C Aydogan, Z E Rassi. J. Chromatogr. A, 2016, 1445:55~61.
57. [57]
  Z Lin, J Pang, H Yang et al. Chem. Commun., 2011, 47(34):9675~9677.
58. [58]
  X Wang, Y Zheng, C Zhang et al. J. Chromatogr. A, 2012, 1239:56~63.
59. [59]
  J Ou, Z Zhang, H Lin et al. Anal. Chim. Acta, 2013, 761:209~216.
60. [60]
  Q Yang, D Huang, S Jin et al. Analyst, 2013, 138(17):4752~4755.
61. [61]
  Y H Shan, L Z Qiao, X Z Shi et al. J. Chromatogr. A, 2015, 1375:101~109.
62. [62]
63. [63]
  J C Zhao, Q Y Zhu, L Y Zhao et al. Analyst, 2016, 141(16):4961~4967.
64. [64]
  M Wu, R Wu, Z Zhang et al. Electrophoresis, 2011, 32(1):105~115.
65. [65]
  J Ou, Z Liu, H Wang et al. Electrophoresis, 2015, 36(1):62~75.
66. [66]
67. [67]
  T Yang, C Ma, H Chen et al. J. Sep. Sci., 2014, 37(5):587~594.
68. [68]
  Y F Zhou, N Z Song, H J Zheng et al. New J. Chem., 2015, 39(12):9714~9721.
69. [69]
  R F Qi, X J Lv, Q Niu et al. New J. Chem., 2015, 39(8):6323~6331.
70. [70]
  Z S Liu, J Liu, Z Y Liu et al. J. Chromatogr. A, 2017, 1498:29~36.
71. [71]
  J Bai, Z Liu, H Wang et al. J. Chromatogr. A, 2017, 1498:37~45.
72. [72]
  K Nagase, J Kobayashi, A Kikuchi et al. RSC Adv., 2015, 5(81):66155~66167.
73. [73]
  H S Wang, X Y Feng, J P Wei. J. Chromatogr. A, 2015, 1409:132~137.
74. [74]
  M Sudheendran, S H Eitel, S Naumann et al. New J. Chem., 2014, 38(11):5597~5607.
75. [75]
  R Bandari, J Kuballa, M R Buchmeiser. J. Sep. Sci., 2013, 36(7):1169~1175.
76. [76]
  R Bandari, M R Buchmeiser. Analyst, 2012, 137(14):3271~3277.
77. [77]
  T Zhou, H Yang, Z Jin et al. J. Sep. Sci., 2016, 39(7):1339~1346.
78. [78]
  A M Yehia, H M Mohamed. J. Sep. Sci., 2016, 39(11):2114:2122.
79. [79]
  T Chaloemsuwiwattanakan, A Sangcakul, C Kitiyakara et al. J. Sep. Sci., 2016, 39(18):3521~3527.
80. [80]
  D S Domingues, I D Souza, M E Queiroz. J. Chromatogr. B, 2015, 993/994:26~35.
81. [81]
  M Mei, X Huang, K Liao et al. Anal. Chim. Acta, 2015, 860:29~36.
82. [82]
  H Zhai, Z Su, Z Chen et al. Anal. Chim. Acta, 2015, 865:16~21.
83. [83]
  B M Carvalho, L M Carvalho, W F Silva Jr. et al. Food Chem., 2014, 154:308~314.
84. [84]
  J Wang, Q Zhao, N Jiang et al. J. Chromatogr. A, 2017, 1485:24~31.
85. [85]
  S Eeltink, S Wouters, J L Dores-Sousa et al. J. Chromatogr. A, 2017, 1498:8~21.
86. [86]
  J Zemenova, D Sykora, H Adamkova et al. J. Sep. Sci., 2017, 40(5):1032~1039.
87. [87]
  H P Jiang, C B Qi, J M Chu et al. Sci. Rep., 2015, 5:7785~7794.
88. [88]
  M Catala-Icardo, S Torres-Cartas, S Meseguer-Lloret et al. Anal. Chim. Acta, 2017, 960:160~167.
89. [89]
  F Yang, Q Bai, K Zhao et al. Anal. Bioanal. Chem., 2015, 407:1721~1734.
90. [90]
  M Ding, Z Wang, R Zheng. Chin. J. Chem., 2010, 28:567~572.
91. [91]
  H Sakamaki, T Uchida, L W Lim et al. J. Chromatogr. A, 2015, 1381:125~131.
92. [92]
  Y Liu, M M Wang, L F Ai et al. J. Sep. Sci., 2014, 37(13):1648~1655.
93. [93]
  J Chen, X Min, P Li et al. Anal. Chim. Acta, 2015, 879:41~47.
94. [94]
  Y L Wang, M Mei, X J Huang et al. Anal. Methods, 2015, 7(2):551~559.
95. [95]
  Y K Lv, Z Y Guo, J Z Wang et al. Anal. Methods, 2015, 7(4):1563~1571.
96. [96]
  Y Shan, X Shi, G Xu. J. Sep. Sci., 2015, 38(6):982~989.
97. [97]
  B Sandig, M R Buchmeiser. ChemSusChem, 2016, 6:1~6.
98. [98]
  T Nema, E C Chan, P C Ho. J. Pharm. Biomed. Anal., 2014, 87:130~141.
99. [99]
  F Svec, Y Lv. Anal. Chem., 2015, 87(1):250~273.
1. [1]
  Fan Wu , Wenchang Tian , Jin Liu , Qiuting Zhang , YanHui Zhong , Zian Lin . Core-Shell Structured Covalent Organic Framework-Coated Silica Microspheres as Mixed-Mode Stationary Phase for High Performance Liquid Chromatography. University Chemistry, 2024, 39(11): 319-326. doi: 10.12461/PKU.DXHX202403031
2. [2]
  Siming Bian , Sijie Luo , Junjie Ou . Application of van Deemter Equation in Instrumental Analysis Teaching: A New Type of Core-Shell Stationary Phase. University Chemistry, 2025, 40(3): 381-386. doi: 10.12461/PKU.DXHX202406087
3. [3]
  Qiuting Zhang , Fan Wu , Jin Liu , Zian Lin . Chromatographic Stationary Phase and Chiral Separation Using Frame Materials. University Chemistry, 2025, 40(4): 291-298. doi: 10.12461/PKU.DXHX202405174
4. [4]
  Yanhui Zhong , Ran Wang , Zian Lin . Analysis of Halogenated Quinone Compounds in Environmental Water by Dispersive Solid-Phase Extraction with Liquid Chromatography-Triple Quadrupole Mass Spectrometry. University Chemistry, 2024, 39(11): 296-303. doi: 10.12461/PKU.DXHX202402017
5. [5]
  Ke Qiu , Fengmei Wang , Mochou Liao , Kerun Zhu , Jiawei Chen , Wei Zhang , Yongyao Xia , Xiaoli Dong , Fei Wang . A Fumed SiO₂-based Composite Hydrogel Polymer Electrolyte for Near-Neutral Zinc-Air Batteries. Acta Physico-Chimica Sinica, 2024, 40(3): 2304036-0. doi: 10.3866/PKU.WHXB202304036
6. [6]
  You Wu , Chang Cheng , Kezhen Qi , Bei Cheng , Jianjun Zhang , Jiaguo Yu , Liuyang Zhang . Efficient Photocatalytic Production of H₂O₂ over ZnO/D-A Conjugated Polymer S-scheme Heterojunction and Charge Transfer Dynamics Investigation. Acta Physico-Chimica Sinica, 2024, 40(11): 2406027-0. doi: 10.3866/PKU.WHXB202406027
7. [7]
  Yuxia Luo , Xiaoyu Xie , Fangfang Chen . 药物递送魔法师——分子印迹聚合物. University Chemistry, 2025, 40(8): 202-210. doi: 10.12461/PKU.DXHX202409129
8. [8]
  Mingyang Men , Jinghua Wu , Gaozhan Liu , Jing Zhang , Nini Zhang , Xiayin Yao . Sulfide Solid Electrolyte Synthesized by Liquid Phase Approach and Application in All-Solid-State Lithium Batteries. Acta Physico-Chimica Sinica, 2025, 41(1): 100004-0. doi: 10.3866/PKU.WHXB202309019
9. [9]
  Zhongxin YU , Wei SONG , Yang LIU , Yuxue DING , Fanhao MENG , Shuju WANG , Lixin YOU . Fluorescence sensing on chlortetracycline of a Zn-coordination polymer based on mixed ligands. Chinese Journal of Inorganic Chemistry, 2024, 40(12): 2415-2421. doi: 10.11862/CJIC.20240304
10. [10]
  Bao Jia , Yunzhe Ke , Shiyue Sun , Dongxue Yu , Ying Liu , Shuaishuai Ding . Innovative Experimental Teaching for the Preparation and Modification of Conductive Organic Polymer Thin Films in Undergraduate Courses. University Chemistry, 2024, 39(10): 271-282. doi: 10.12461/PKU.DXHX202404121
11. [11]
  Xiao SANG , Qi LIU , Jianping LANG . Synthesis, structure, and fluorescence properties of Zn(Ⅱ) coordination polymers containing tetra-alkenylpyridine ligands. Chinese Journal of Inorganic Chemistry, 2024, 40(11): 2124-2132. doi: 10.11862/CJIC.20240158
12. [12]
  Xuefei Leng , Yanshai Wang , Hai Wang , Shengyang Tao . The In-Depth integration of “Industry-University-Research” in the Exploration and Practice of “Comprehensive Training in Polymer Engineering”. University Chemistry, 2025, 40(4): 66-71. doi: 10.12461/PKU.DXHX202405105
13. [13]
  Ruiying WANG , Hui WANG , Fenglan CHAI , Zhinan ZUO , Benlai WU . Three-dimensional homochiral Eu(Ⅲ) coordination polymer and its amino acid configuration recognition. Chinese Journal of Inorganic Chemistry, 2025, 41(5): 877-884. doi: 10.11862/CJIC.20250052
14. [14]
  Minghui Wu , Markus Mühlinghaus , Xuechao Li , Chaojie Xu , Qiang Chen , Haiming Zhang , Klaus Müllen , Lifeng Chi . On-Surface Synthesis of Chevron-Shaped Conjugated Ladder Polymers Consisting of Benzo[a]azulene Units. Acta Physico-Chimica Sinica, 2024, 40(8): 2307024-0. doi: 10.3866/PKU.WHXB202307024
15. [15]
  Runjie Li , Hang Liu , Xisheng Wang , Wanqun Zhang , Wanqun Hu , Kaiping Yang , Qiang Zhou , Si Liu , Pingping Zhu , Wei Shao . 氨基酸的衍生及手性气相色谱分离创新实验. University Chemistry, 2025, 40(6): 286-295. doi: 10.12461/PKU.DXHX202407059
16. [16]
  Junjie Zhang , Yue Wang , Qiuhan Wu , Ruquan Shen , Han Liu , Xinhua Duan . Preparation and Selective Separation of Lightweight Magnetic Molecularly Imprinted Polymers for Trace Tetracycline Detection in Milk. University Chemistry, 2024, 39(5): 251-257. doi: 10.3866/PKU.DXHX202311084
17. [17]
  Fanpeng Meng , Fei Zhao , Jingkai Lin , Jinsheng Zhao , Huayang Zhang , Shaobin Wang . Optimizing interfacial electric fields in carbon nitride nanosheet/spherical conjugated polymer S-scheme heterojunction for hydrogen evolution. Acta Physico-Chimica Sinica, 2025, 41(8): 100095-0. doi: 10.1016/j.actphy.2025.100095
18. [18]
  Xingchao Zhao , Xiaoming Li , Ming Liu , Zijin Zhao , Kaixuan Yang , Pengtian Liu , Haolan Zhang , Jintai Li , Xiaoling Ma , Qi Yao , Yanming Sun , Fujun Zhang . Photomultiplication-Type All-Polymer Photodetectors and Their Applications in Photoplethysmography Sensor. Acta Physico-Chimica Sinica, 2025, 41(1): 100007-0. doi: 10.3866/PKU.WHXB202311021
19. [19]
  Hanmei Lü , Xin Chen , Qifu Sun , Ning Zhao , Xiangxin Guo . Uniform Garnet Nanoparticle Dispersion in Composite Polymer Electrolytes. Acta Physico-Chimica Sinica, 2024, 40(3): 2305016-0. doi: 10.3866/PKU.WHXB202305016
20. [20]
  Dongdong Yao , JunweiGu , Yi Yan , Junliang Zhang , Yaping Zheng . Teaching Phase Separation Mechanism in Polymer Blends Using Process Representation Teaching Method: A Teaching Design for Challenging Theoretical Concepts in “Polymer Structure and Properties” Course. University Chemistry, 2025, 40(4): 131-137. doi: 10.12461/PKU.DXHX202408125

Get Citation

PDF

XML

Metrics

PDF Downloads(8)
Abstract views(687)
HTML views(115)

通讯作者: 陈斌, bchen63@163.com

1.
沈阳化工大学材料科学与工程学院沈阳 110142