Citation: Wu Yongjie, Shi Bingfeng. Transition Metal-Catalyzed C-H Activation via Imine-Based Transient Directing Group Strategy[J]. Chinese Journal of Organic Chemistry, ;2020, 40(11): 3517-3535. doi: 10.6023/cjoc202003057 shu

Transition Metal-Catalyzed C-H Activation via Imine-Based Transient Directing Group Strategy

Wu Yongjie ,
Shi Bingfeng ^,

Department of Chemistry, Zhejiang University, Hangzhou 310027

Corresponding author: Shi Bingfeng, bfshi@zju.edu.cn
Received Date: 25 March 2020
Revised Date: 30 April 2020
Available Online: 11 April 2020
Fund Project: Natural Science Foundation of Zhejiang Province LR17B02000Fundamental Research Funds for the Central Universities 2018XZZX001-02National Natural Science Foundation of China 21925109Outstanding Young Talents of Zhejiang Province ZJWR0108Project supported by the National Natural Science Foundation of China (Nos. 21925109, 21772170), the Outstanding Young Talents of Zhejiang Province (No. ZJWR0108), the Fundamental Research Funds for the Central Universities (No. 2018XZZX001-02) and the Natural Science Foundation of Zhejiang Province (No. LR17B020001)National Natural Science Foundation of China 21772170

Figures(50)

In the past decades, transition metal-catalyzed C—H activation has experienced tremendous growth and revolutionized the field of organic synthesis. Several elegant strategies have been developed to promote reactivity and control precise site-selectivity. Among which, transient directing group strategy has been recognized to be an efficient and powerful approach for selective C—H functionalization. In contrast to traditional directing groups with covalent linkage, transient directing group strategy circumvents the covalent installation and removal of directing groups, which significantly improve the synthetic efficiency and broaden the range of synthetic applications. The recent advances in imine-based transition directing groups are summarized, providing an overview of recent achievements in this cutting-edge research field over the past few years. For clarity, it is classified into two sections according to the type of substrate and the type of activated hydrocarbon bond. Emphasis is placed on the fully discussion of various transient directing groups and their applications. Finally, the limitations of previous works and perspectives on this cutting-edge area are also described.
- transient directing group strategy,
- transition metal,
- C-H activation,
- imine,
- directing groups
1. [1]
  (a) Godula, K.; Sames, D. Science 2006, 312, 67.
  (b) Bergman, R. G. Nature 2007, 446, 391.
  (c) Ellman, J. A.; Ackermann, L.; Shi, B. F. J. Org. Chem. 2019, 84, 12701.
2. [2]
3. [3]
  (a) Zhang, M.; Zhang, Y.; Jie, X.; Zhao, H.; Li, G.; Su, W. Org. Chem. Front. 2014, 1, 843.
  (b) Sambiagio, C.; Schönbauer, D.; Blieck, R.; Dao-Huy, T.; Pototschnig, G.; Schaaf, P.; Wiesinger, T.; Zia, M. F.; Wencel-Delord, J.; Besset, T.; Maes, B. U. W.; Schnürch, M. Chem. Soc. Rev. 2018, 47, 6603.
  (c) Zhang, Q.; Shi, B.-F. Chin. J. Chem. 2019, 37, 647.
  (d) Rej, S.; Ano, Y.; Chatani, N. Chem. Rev. 2020, 120, 1788.
4. [4]
5. [5]
  For selected examples of phosphites as transient directing groups, see:
  (a) Bedford, R. B.; Coles, S. J.; Hursthouse, M. B.; Limmert, M. E. Angew. Chem., Int. Ed. 2003, 42, 112.
  (b) Bedford, R. B.; Limmert, M. E. J. Org. Chem. 2003, 68, 8669.
  (c) Bedford, R. B.; Betham, M.; Caffyn, A. J.; Charmant, J. P.; Lewis-Alleyne, L. C.; Long, P. D.; Polo-Ceron, D.; Prashar, S. Chem. Commun. 2008, 990.
  (d) Bedford, R. B.; Haddow, M. F.; Webster, R. L.; Mitchell, C. J. Org. Biomol. Chem. 2009, 7, 3119.
  (e) Carrion, M. C.; Cole-Hamilton, D. J. Chem. Commun. 2006, 4527.
  (f) Lewis, J. C.; Wu, J.; Bergman, R. G.; Ellman, J. A. Organometallics 2005, 24, 5737.
  (g) Oi, S.; Watanabe, S.-I.; Fukita, S.; Inoue, Y. Tetrahedron Lett. 2003, 44, 8665.
  (h) Yang, J. F.; Wang, R. H.; Wang, Y. X.; Yao, W. W.; Liu, Q. S.; Ye, M. Angew. Chem., Int. Ed. 2016, 55, 14116.
  (i) Liu, Q.-S.; Wang, D.-Y.; Yang, J.-F.; Ma, Z.-Y.; Ye, M. Tetrahedron 2017, 73, 3591.
6. [6]
  Mo, F.; Dong, G. Science 2014, 345, 68. doi: 10.1126/science.1254465
7. [7]
  For selected examples of transient enamine directing groups, see:
  (a) Wang, Z.; Reinus, B. J.; Dong, G. J. Am. Chem. Soc. 2012, 134, 13954.
  (b) Mo, F.; Lim, H. N.; Dong, G. J. Am. Chem. Soc. 2015, 137, 15518.
  (c) Xu, Y.; Young, M. C.; Dong, G. J. Am. Chem. Soc. 2017, 139, 5716.
  (d) Lim, H. N.; Dong, G. Angew. Chem., Int. Ed. 2015, 54, 15294.
  (e) Xu, Y.; Su, T.; Huang, Z.; Dong, G. Angew. Chem., Int. Ed. 2016, 55, 2559.
8. [8]
  Jun, C.-H.; Lee, H.; Hong, J.-B. J. Org. Chem. 1997, 62, 1200. doi: 10.1021/jo961887d
9. [9]
  Jun, C.-H.; Lee, D.-Y.; Hong, J.-B. Tetrahedron Lett. 1997, 38, 6673. doi: 10.1016/S0040-4039(97)01562-1
10. [10]
  Vautravers, N. R.; Regent, D. D.; Breit, B. Chem. Commun. 2011, 47, 6635. doi: 10.1039/c1cc10683j
11. [11]
  Beletskiy, E. V.; Sudheer, C.; Douglas, C. J. J. Org. Chem. 2012, 77, 5884. doi: 10.1021/jo300779q
12. [12]
  Jun, C.-H.; Moon, C. W.; Hong, J.-B.; Lim, S.-G.; Chung, K.-Y.; Kim, Y.-H. Chem.-Eur. J. 2002, 8, 485. doi: 10.1002/1521-3765(20020118)8:2<485::AID-CHEM485>3.0.CO;2-1
13. [13]
  Kuninobu, Y.; Nishina, Y.; Shouho, M.; Takai, K. Angew. Chem., Int. Ed. 2006, 45, 2766. doi: 10.1002/anie.200503627
14. [14]
  Chen, S.; Yu, J.; Jiang, Y.; Chen, F.; Cheng, J. Org. Lett. 2013, 15, 4754. doi: 10.1021/ol4021145
15. [15]
  Tan, P. W.; Juwaini, N. A. B.; Seayad, J. Org. Lett. 2013, 15, 5166. doi: 10.1021/ol402145m
16. [16]
  Li, G.; Jiang, J.; Xie, H.; Wang, J. Chem.-Eur. J. 2019, 25, 4688. doi: 10.1002/chem.201900762
17. [17]
  Liu, X. H.; Park, H.; Hu, J. H.; Hu, Y.; Zhang, Q. L.; Wang, B. L.; Sun, B.; Yeung, K. S.; Zhang, F. L.; Yu, J. Q. J. Am. Chem. Soc. 2017, 139, 888. doi: 10.1021/jacs.6b11188
18. [18]
  Chen, X. Y.; Ozturk, S.; Sorensen, E. J. Org. Lett. 2017, 19, 1140. doi: 10.1021/acs.orglett.7b00161
19. [19]
  Xu, J.; Liu, Y.; Wang, Y.; Li, Y.; Xu, X.; Jin, Z. Org. Lett. 2017, 19, 1562. doi: 10.1021/acs.orglett.7b00363
20. [20]
  Hu, W.; Zheng, Q.; Sun, S.; Cheng, J. Chem. Commun. 2017, 53, 6263. doi: 10.1039/C7CC03006A
21. [21]
  Li, B.; Seth, K.; Niu, B.; Pan, L.; Yang, H.; Ge, H. Angew. Chem., Int. Ed. 2018, 57, 3401. doi: 10.1002/anie.201713357
22. [22]
  Wang, D. Y.; Guo, S. H.; Pan, G. F.; Zhu, X. Q.; Gao, Y. R.; Wang, Y. Q. Org. Lett. 2018, 20, 1794. doi: 10.1021/acs.orglett.8b00292
23. [23]
  Wang, Y. F.; Xu, W. G.; Sun, B.; Yu, Q. Q.; Li, T. J.; Zhang, F. L. J. Org. Chem. 2019, 84, 13104. doi: 10.1021/acs.joc.9b02139
24. [24]
  Chen, X. Y.; Sorensen, E. J. J. Am. Chem. Soc. 2018, 140, 2789. doi: 10.1021/jacs.8b00048
25. [25]
  (a) Li, F.; Zhou, Y.; Yang, H.; Liu, D.; Sun, B.; Zhang, F. L. Org. Lett. 2018, 20, 146.
  (b) Zhan, B.-B.; Li, Y.; Xu, J.-W.; Nie, X.-L.; Fan, J.; Jin, L.; Shi, B.-F. Angew. Chem., Int. Ed. 2018, 57, 5858.
26. [26]
  (a) Baudoin, O. Eur. J. Org. Chem. 2005, 4223.
  (b) Bringmann, G.; Price Mortimer, A. J.; Keller, P. A.; Gresser, M. J.; Garner, J.; Breuning, M. Angew. Chem., Int. Ed. 2005, 44, 5384.
  (c) Wencel-Delord, J.; Panossian, A; Leroux, F. R.; Colobert, F. Chem. Soc. Rev. 2015, 44, 3418.
  (d) Ma, G.; Sibi, M. P. Chem.-Eur. J. 2015, 21, 11644.
  (e) Kumarasamy, E.; Raghunathan, R.; Sibi, M. P.; Sivaguru, J. Chem. Rev. 2015, 115, 11239.
  (f) Mori, K.; Itakura, T.; Akiyama, T. Angew. Chem., Int. Ed. 2016, 55, 11642.
  (g) Xu, C.; Zheng, H.; Hu, B.; Liu, X.; Liu, L.; Feng, X. Chem. Commun. 2017, 53, 9741.
  (h) Zilate, B.; Castrogiovanni, A.; Sparr, C. ACS Catal. 2018, 8, 2981.
  (i) Liao, G.; Zhou, T.; Yao, Q.-J.; Shi, B.-F. Chem. Commun. 2019, 55, 8514.
27. [27]
  (a) Yao, Q. J.; Zhang, S.; Zhan, B. B.; Shi, B. F. Angew. Chem., Int. Ed. 2017, 56, 6617.
  (b) Fan, J.; Yao, Q. J.; Liu, Y. H.; Liao, G.; Zhang, S.; Shi, B. F. Org. Lett. 2019, 21, 3352.
28. [28]
  (a) Wang, Q.; Gu, Q.; You, S.-L. Angew. Chem., Int. Ed. 2019, 58, 6818.
  (b) Chen, J.; Liu, Y. E.; Gong, X.; Shi, L.; Zhao, B. Chin. J. Chem. 2019, 37, 103.
  (c) Gong, L.-Z. Sci. China: Chem. 2019, 62, 3.
  (d) Li, S.; Chen, X.-Y.; Enders, D. Chem 2018, 4, 2026
29. [29]
  (a) Liao, G.; Yao, Q. J.; Zhang, Z. Z.; Wu, Y. J.; Huang, D. Y.; Shi, B. F. Angew. Chem., Int. Ed. 2018, 57, 3661.
  (b) Liao, G.; Li, B.; Chen, H. M.; Yao, Q. J.; Xia, Y. N.; Luo, J.; Shi, B. F. Angew. Chem., Int. Ed. 2018, 57, 17151.
30. [30]
  Liao, G.; Chen, H. M.; Xia, Y. N.; Li, B.; Yao, Q. J.; Shi, B. F. Angew. Chem., Int. Ed. 2019, 58, 11464. doi: 10.1002/anie.201906700
31. [31]
  Zhang, S.; Liao, G.; Shi, B. Chin. J. Org. Chem. 2019, 39, 1522(in Chinese).
32. [32]
  (a) Zhang, S.; Yao, Q.-J.; Liao, G.; Li, X.; Li, H.; Chen, H.-M.; Hong, X.; Shi, B.-F. ACS Catal. 2019, 9, 1956.
  (b) Chen, H.-M.; Zhang, S.; Liao, G.; Yao, Q.-J.; Xu, X.-T.; Zhang, K.; Shi, B.-F. Organometallics 2019, 38, 4022.
  (c) Zhang, J.; Xu, Q.; Wu, J.; Fan, J.; Xie, M. Org. Lett. 2019, 21, 6361.
33. [33]
  Jin, L.; Yao, Q.-J.; Xie, P.-P.; Li, Y.; Zhan, B.-B.; Han, Y.-Q.; Hong, X.; Shi, B.-F. Chem 2020, 6, 497 doi: 10.1016/j.chempr.2019.12.011
34. [34]
  Song, H.; Li, Y.; Yao, Q. J.; Jin, L.; Liu, L.; Liu, Y. H.; Shi, B. F. Angew. Chem., Int. Ed. 2020, 59, 6576. doi: 10.1002/anie.201915949
35. [35]
  Xu, J.; Liu, Y.; Zhang, J.; Xu, X.; Jin, Z. Chem. Commun. 2018, 54, 689. doi: 10.1039/C7CC09273C
36. [36]
  Zhang, F.-L.; Hong, K.; Li, T.-J.; Park, H.; Yu, J.-Q. Science 2016, 351, 252. doi: 10.1126/science.aad7893
37. [37]
  (a) Ma, F.; Lei, M.; Hu, L. Org. Lett. 2016, 18, 2708.
  (b) Chen, J.; Bai, C.; Ma, H.; Liu, D.; Bao, Y.-S. Chin. Chem. Lett. 2020, DOI: 10.1016/j.cclet.2020.02.055.
38. [38]
  Park, H.; Yoo, K.; Jung, B.; Kim, M. Tetrahedron 2018, 74, 2048. doi: 10.1016/j.tet.2018.03.006
39. [39]
  Tang, M.; Yu, Q.; Wang, Z.; Zhang, C.; Sun, B.; Yi, Y.; Zhang, F. L. Org. Lett. 2018, 20, 7620. doi: 10.1021/acs.orglett.8b03359
40. [40]
  Yang, K.; Li, Q.; Liu, Y.; Li, G.; Ge, H. J. Am. Chem. Soc. 2016, 138, 12775. doi: 10.1021/jacs.6b08478
41. [41]
  St John-Campbell, S.; White, A. J. P.; Bull, J. A. Chem. Sci. 2017, 8, 4840. doi: 10.1039/C7SC01218G
42. [42]
  Hong, K.; Park, H.; Yu, J. Q. ACS Catal. 2017, 7, 6938. doi: 10.1021/acscatal.7b02905
43. [43]
  Pan, L.; Yang, K.; Li, G.; Ge, H. Chem. Commun. 2018, 54, 2759. doi: 10.1039/C8CC00980E
44. [44]
  Zhang, Y.-F.; Wu, B.; Shi, Z.-J. Chem.-Eur. J. 2016, 22, 17808. doi: 10.1002/chem.201603805
45. [45]
  Mu, D.; Wang, X.; Chen, G.; He, G. J. Org. Chem. 2017, 82, 4497. doi: 10.1021/acs.joc.7b00531
46. [46]
  Wang, X.; Song, S.; Jiao, N. Chin. J. Chem. 2018, 36, 213. doi: 10.1002/cjoc.201700726
47. [47]
  Rasheed, O. Synlett 2018, 29, 1033. doi: 10.1055/s-0036-1591765
48. [48]
  Huang, J.; Ding, J.; Ding, T. M.; Zhang, S.; Wang, Y.; Sha, F.; Zhang, S. Y.; Wu, X. Y.; Li, Q. Org. Lett. 2019, 21, 7342. doi: 10.1021/acs.orglett.9b02632
49. [49]
  Park, H.; Verma, P.; Hong, K.; Yu, J. Q. Nat. Chem. 2018, 10, 755. doi: 10.1038/s41557-018-0048-1
50. [50]
  Chen, X. Y.; Ozturk, S.; Sorensen, E. J. Org. Lett. 2017, 19, 6280. doi: 10.1021/acs.orglett.7b02906
51. [51]
  Li, F.; Zhou, Y.; Yang, H.; Wang, Z.; Yu, Q.; Zhang, F.-L. Org. Lett. 2019, 21, 3692. doi: 10.1021/acs.orglett.9b01158
52. [52]
  Yong, Q.; Sun, B.; Zhang, F.-L. Tetrahedron Lett. 2019, 60, 151263. doi: 10.1016/j.tetlet.2019.151263
53. [53]
  Qiao, H.; Sun, B.; Yu, Q.; Huang, Y.-Y.; Zhou, Y.; Zhang, F.-L. Org. Lett. 2019, 21, 6914. doi: 10.1021/acs.orglett.9b02530
54. [54]
  Wu, Y.-J.; Yao, Q.-J.; Chen, H.-M.; Liao, G.; Shi, B.-F. Sci. China:Chem. 2020, 63, 875.
55. [55]
  Liu, Y.; Ge, H. Nat. Chem. 2016, 9, 26.
56. [56]
  (a) Xu, J.-W.; Zhang, Z.-Z.; Rao, W.-H.; Shi, B.-F. J. Am. Chem. Soc. 2016, 138, 10750.
  (b) Zhan, B.-B.; Li, Y.; Xu, J.-W.; Nie, X.-L.; Fan, J.; Jin, L.; Shi, B.-F. Angew. Chem., Int. Ed. 2018, 57, 5858.
57. [57]
  Xu, Y.; Young, M. C.; Wang, C.; Magness, D. M.; Dong, G. Angew. Chem., Int. Ed. 2016, 55, 9084. doi: 10.1002/anie.201604268
58. [58]
  Wu, Y.; Chen, Y. Q.; Liu, T.; Eastgate, M. D.; Yu, J. Q. J. Am. Chem. Soc. 2016, 138, 14554. doi: 10.1021/jacs.6b09653
59. [59]
  Yada, A.; Liao, W.; Sato, Y.; Murakami, M. Angew. Chem., Int. Ed. 2017, 56, 1073. doi: 10.1002/anie.201610666
60. [60]
  Chen, Y.-Q.; Wang, Z.; Wu, Y.; Wisniewski, S. R.; Qiao, J. X.; Ewing, W. R.; Eastgate, M. D.; Yu, J.-Q. J. Am. Chem. Soc. 2018, 140, 17884. doi: 10.1021/jacs.8b07109
61. [61]
  (a) Vicente, J.; Saura-Llamas, I.; Palin, M. G.; Jones, P. G.; Ramírez de Arellano, M. C. Organometallics 1997, 16, 826.
  (b) Largeron, M. Eur. J. Org. Chem. 2013, 2013, 5225.
  (c) Corey, E. J.; Achiwa, K. J. Am. Chem. Soc. 1969, 91, 1429.
  (d) Hartwig, J. F.; Richards, S.; Barañano, D.; Paul, F. J. Am. Chem. Soc. 1996, 118, 3626.
  (e) Wolfe, J. P.; Wagaw, S.; Buchwald, S. L. J. Am. Chem. Soc. 1996, 118, 7215.
  (f) Ryland, B. L.; Stahl, S. S. Angew. Chem., Int. Ed. 2014, 53, 8824.
62. [62]
  (a) Liu, L.; Liu, Y.-H.; Shi, B.-F. Chem. Sci. 2020, 11, 290.
  (b) Xu, J.-W.; Zhang, Z.-Z.; Rao, W.-H.; Shi, B.-F. J. Am. Chem. Soc. 2016, 138, 10750.
63. [63]
  Xiao, L.-J.; Hong, K.; Luo, F.; Hu, L.; Ewing, W. R.; Yeung, K.-S.; Yu, J.-Q. Angew. Chem., Int. Ed. 2020, 59, 9594. doi: 10.1002/anie.202000532
64. [64]
  (a) Chen, G.; Gong, W.; Zhuang, Z.; Andrä, M. S.; Chen, Y.-Q.; Hong, X.; Yang, Y.-F.; Liu, T.; Houk, K. N.; Yu, J.-Q. Science 2016, 353, 1023.
  (b) Yan, S.-Y.; Han, Y.-Q.; Yao, Q.-J.; Nie, X.-L.; Liu, L.; Shi, B.-F. Angew. Chem., Int. Ed. 2018, 57, 9093.
  (c) Han, Y.-Q.; Ding, Y.; Zhou, T.; Yan, S.-Y.; Song, H.; Shi, B.-F. J. Am. Chem. Soc. 2019, 141, 4558.
  (d) Zhou, T.; Jiang, M.-X.; Yang, X.; Yue, Q.; Han, Y.-Q.; Ding, Y.; Shi, B.-F. Chin. J. Chem. 2020, 38, 242.
1. [1]
  Yan Qi , Yueqin Yu , Weisi Guo , Yongjun Liu . 过渡金属参与的有机反应案例教学与实践探索. University Chemistry, 2025, 40(6): 111-117. doi: 10.12461/PKU.DXHX202411021
2. [2]
  Feng Zheng , Ruxun Yuan , Xiaogang Wang . “Research-Oriented” Comprehensive Experimental Design in Polymer Chemistry: the Case of Polyimide Aerogels. University Chemistry, 2024, 39(10): 210-218. doi: 10.12461/PKU.DXHX202404027
3. [3]
  Kaimin WANG , Xiong GU , Na DENG , Hongmei YU , Yanqin YE , Yulu MA . Synthesis, structure, fluorescence properties, and Hirshfeld surface analysis of three Zn(Ⅱ)/Cu(Ⅱ) complexes based on 5-(dimethylamino) isophthalic acid. Chinese Journal of Inorganic Chemistry, 2024, 40(7): 1397-1408. doi: 10.11862/CJIC.20240009
4. [4]
  Yuanyuan Ping , Wangqing Kong . 光催化碳氢键官能团化合成1-苯基-1,2-乙二醇. University Chemistry, 2025, 40(6): 238-247. doi: 10.12461/PKU.DXHX202408092
5. [5]
  Xiwen Xing , Muyi Guo , Zhuoran Hu , Shunchun Yao , Yao Sun . Context-Driven Teaching with Cue-Guided Reasoning: Taking X-Ray Teaching Practice as an Example. University Chemistry, 2025, 40(7): 141-147. doi: 10.12461/PKU.DXHX202409097
6. [6]
  Jianquan Liu , Xiangshan Wang . Teaching Design and Practice of Naming Rules for Circular Isomer Configuration under the Guidance of Information Literacy. University Chemistry, 2025, 40(7): 352-358. doi: 10.12461/PKU.DXHX202409082
7. [7]
  Yikai Wang , Xiaolin Jiang , Haoming Song , Nan Wei , Yifan Wang , Xinjun Xu , Cuihong Li , Hao Lu , Yahui Liu , Zhishan Bo . Thickness-Insensitive, Cyano-Modified Perylene Diimide Derivative as a Cathode Interlayer Material for High-Efficiency Organic Solar Cells. Acta Physico-Chimica Sinica, 2025, 41(3): 2406007-0. doi: 10.3866/PKU.WHXB202406007
8. [8]
  Yuqiao Zhou , Weidi Cao , Shunxi Dong , Lili Lin , Xiaohua Liu . Study on the Teaching Reformation of Practical X-ray Crystallography. University Chemistry, 2024, 39(3): 23-28. doi: 10.3866/PKU.DXHX202303003
9. [9]
  Bingliang Li , Yuying Han , Dianyang Li , Dandan Liu , Wenbin Shang . One-Step Synthesis of Benorilate Guided by Green Chemistry Principles and in vivo Dynamic Evaluation. University Chemistry, 2024, 39(6): 342-349. doi: 10.3866/PKU.DXHX202311070
10. [10]
  Fangfang Chen , Haiming Fan , Yan Li , Yuan He . 化学生物学专业多元化人才培养导向的课程体系优化探索. University Chemistry, 2025, 40(8): 92-99. doi: 10.12461/PKU.DXHX202409108
11. [11]
  Ruizhi Duan , Xiaomei Wang , Panwang Zhou , Yang Liu , Can Li . The role of hydroxyl species in the alkaline hydrogen evolution reaction over transition metal surfaces. Acta Physico-Chimica Sinica, 2025, 41(9): 100111-0. doi: 10.1016/j.actphy.2025.100111
12. [12]
  Jiatong Hu , Qiyi Wang , Ruiwen Tang , Jiajing Feng . Photocatalytic Journey of Perylene Diimides in a Competitive Arena. University Chemistry, 2025, 40(5): 328-333. doi: 10.12461/PKU.DXHX202407015
13. [13]
  Geyang Song , Dong Xue , Gang Li . Recent Advances in Transition Metal-Catalyzed Synthesis of Anilines from Aryl Halides. University Chemistry, 2024, 39(2): 321-329. doi: 10.3866/PKU.DXHX202308030
14. [14]
  Jing WU , Puzhen HUI , Huilin ZHENG , Pingchuan YUAN , Chunfei WANG , Hui WANG , Xiaoxia GU . Synthesis, crystal structures, and antitumor activities of transition metal complexes incorporating a naphthol-aldehyde Schiff base ligand. Chinese Journal of Inorganic Chemistry, 2024, 40(12): 2422-2428. doi: 10.11862/CJIC.20240278
15. [15]
  Lu Zhuoran , Li Shengkai , Lu Yuxuan , Wang Shuangyin , Zou Yuqin . Cleavage of C―C Bonds for Biomass Upgrading on Transition Metal Electrocatalysts. Acta Physico-Chimica Sinica, 2024, 40(4): 2306003-0. doi: 10.3866/PKU.WHXB202306003
16. [16]
  Fei Xie , Chengcheng Yuan , Haiyan Tan , Alireza Z. Moshfegh , Bicheng Zhu , Jiaguo Yu . d-Band Center Regulated O₂ Adsorption on Transition Metal Single Atoms Loaded COF: A DFT Study. Acta Physico-Chimica Sinica, 2024, 40(11): 2407013-0. doi: 10.3866/PKU.WHXB202407013
17. [17]
  Yongmin Zhang , Shuang Guo , Mingyue Zhu , Menghui Liu , Sinong Li . Design and Improvement of Physicochemical Experiments Based on Problem-Oriented Learning: a Case Study of Liquid Surface Tension Measurement. University Chemistry, 2024, 39(2): 21-27. doi: 10.3866/PKU.DXHX202307026
18. [18]
  Qiying Xia , Guokui Liu , Yunzhi Li , Yaoyao Wei , Xia Leng , Guangli Zhou , Aixiang Wang , Congcong Mi , Dengxue Ma . Construction and Practice of “Teaching-Learning-Assessment Integration” Model Based on Outcome Orientation: Taking “Structural Chemistry” as an Example. University Chemistry, 2024, 39(10): 361-368. doi: 10.3866/PKU.DXHX202311007
19. [19]
  Guoqiang Chen , Zixuan Zheng , Wei Zhong , Guohong Wang , Xinhe Wu . Molten Intermediate Transportation-Oriented Synthesis of Amino-Rich g-C₃N₄ Nanosheets for Efficient Photocatalytic H₂O₂ Production. Acta Physico-Chimica Sinica, 2024, 40(11): 2406021-0. doi: 10.3866/PKU.WHXB202406021
20. [20]
  Fa Wang , Yu Chen , Hui Chao . Ruthenium(II) Complexes as Photoactivated Chemo-Prodrugs for Hypoxic Tumor Therapy. University Chemistry, 2025, 40(7): 200-212. doi: 10.12461/PKU.DXHX202410024

Get Citation

PDF

XML

Metrics

PDF Downloads(87)
Abstract views(4930)
HTML views(1024)

通讯作者: 陈斌, bchen63@163.com

1.
沈阳化工大学材料科学与工程学院沈阳 110142