Citation: Wu Jinghua, Wang Cheng, Chen Pengquan, Ma Zhiqiang. Synthetic Progress of Natural Products Gracilioethers and Hippolachnin A[J]. Chinese Journal of Organic Chemistry, ;2020, 40(10): 3289-3299. doi: 10.6023/cjoc202003014 shu

Synthetic Progress of Natural Products Gracilioethers and Hippolachnin A

Key Laboratory of Functional Molecular Engineering of Guangdong Province, School of Chemistry & Chemical Engineering, South China University of Technology, Guangzhou 510641

Corresponding author: Ma Zhiqiang, cezqma@scut.edu.cn
Received Date: 6 March 2020
Revised Date: 8 April 2020
Available Online: 17 April 2020
Fund Project: the National Program on Key Research Project 2016YFA0602900the National Natural Science Foundation of China 21871098the National Natural Science Foundation of China 21672073Project supported by the National Program on Key Research Project (No. 2016YFA0602900), the Science and Technology Program of Guangzhou City (No. 201707010073) and the National Natural Science Foundation of China (Nos. 21672073, 21871098)the Science and Technology Program of Guangzhou City 201707010073

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Gracilioethers and hippolachnin A were isolated from marine sponge. Gracilioethers showed antimalarial activity while hippolachnin A exhibited strong antifungal activity. Their fascinating structures and outstanding biological activities have attracted attentions from chemists. Progress on the synthesis of gracilioethers with tricyclic skeleton and hippolachnin A are reviewed in terms of the key strategies employed.
- gracilioether,
- hippolachnin A,
- natural product,
- total synthesis
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