Citation: Xie Huanping, Wu Bo, Chen Muwang, Yu Changbin, Li Hongwang, Li Xiang, Zhou Yonggui. Enantioselective Synthesis of Triarylmethanes Bearing Pyrazole Moiety through Squaramide-Catalyzed Addition of Azadienes with Pyrazolin-5-ones[J]. Chinese Journal of Organic Chemistry, ;2020, 40(10): 3452-3462. doi: 10.6023/cjoc202003005 shu

Enantioselective Synthesis of Triarylmethanes Bearing Pyrazole Moiety through Squaramide-Catalyzed Addition of Azadienes with Pyrazolin-5-ones

Xie Huanping ^b ,
Wu Bo ^b ,
Chen Muwang ^b ,
Yu Changbin ^b ,
Li Hongwang ^b ,
Li Xiang ^a ,
Zhou Yonggui ^a,b,,

a.
Zhang Dayu School of Chemistry, Dalian University of Technology, Dalian 116024
b.
State Key Laboratory of Catalysis, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116023

Corresponding author: Zhou Yonggui, ygzhou@dicp.ac.cn
Received Date: 3 March 2020
Revised Date: 27 March 2020
Available Online: 13 April 2020
Fund Project: Project supported by the National Natural Science Foundation of China (No. 21690074)the National Natural Science Foundation of China 21690074

Figures(8)

Using cinchona-derived bifunctional squaramides as catalyst, an asymmetric addition of aurone-derived azadienes with pyrazolin-5-ones was developed, providing a series of chiral triarylmethanes bearing pyrazole moiety with up to 99% ee.
- triarylmethane,
- pyrazole,
- organocatalysis,
- azadiene,
- enantioselective addition
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