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Citation: Bao De-Cai, Zhang Qiong-Gang, Liu Xiu-Dong, Ma Xiao-Jun, Yuan Quan. Preparation of VE Microcapsules and Its Controlled Release Characteristics[J]. Acta Physico-Chimica Sinica, ;2004, 20(02): 178-181. doi: 10.3866/PKU.WHXB20040214 shu

Preparation of VE Microcapsules and Its Controlled Release Characteristics

1.
Laboratory of Biomedical Material Engineering, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian　116023; School of Science of Chemistry and Food, Bohai University, Jinzhou　121000

Received Date: 4 August 2003
Available Online: 15 February 2004

Monodisperse polystyrene(PS) microcapsules containing vitamin E(VE)were prepared by membrane emulsification-dying in liquid technique. The diameter of microcapsules was about 4 times the size of the pore diameter of Shirasu porous glass (SPG) membrane, and the coefficient of variation (CV) of the microcapsule size was less than 0.2, showing a od monodispersity. Furthermore, the effects of the ratio of PS to VE (m/m) and the diameter of microcapsules on the release characteristics were investigated. When the ratio of PS to VE (m/m) is 40/1, the permeability coefficients were 0.71×10－9 and 0.74×10－9 m•s－1 corresponding to the microcapsule diameters of 21.32 and 11.45 μm, and the concentrations of VE released were 8 and 12 mg•L－1 respectively, which conform to the optimal concentration in applications.
- Membrane emulsification;Drying in liquid;Vitamin E;Microcapsule;　Controlled release
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