Citation:
Shen Yu-Hua, Yang Zhan-Lan, Wu Jin-Guang. FT-IR for the Soluble Complexes of Bovine Serum Albumin Reacted with Calcium Hydroxyapatites[J]. Acta Physico-Chimica Sinica,
;1999, 15(12): 1064-1069.
doi:
10.3866/PKU.WHXB19991203
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Calcium hydroxyapatite [Ca 10 (OH) 2(PO 4) 6]and protein are main compositions of bones and tooth of animals. The interaction of protein with calcium hydroxyapatite plays an important role in biomineralization process. In this paper, a series of soluble bovine serum albumin (BSA)-calcium hydroxyapatite complexes in aqueous solution produced by different initial mole ratio of solid calcium hydroxyapatite and BSA were studied using FTIR spectroscopy. The results show that the composition of the soluble BSA-calcium hydroxyapatite complexes is nonstoichiometric. Calcium hydroxyapatite may be involved in hydrogen bonding to and coordinating with BSA in the soluble complexes. The interaction of BSA with calcium hydroxyapatite increased the solubility of calcium hydroxyapatite in aqueous solution, which is helpful for the formation of self organized structure of protein calcium hydroxyapatite complexes.
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