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Citation: Yaling Chen. Basic Theory and Competitive Exam Analysis of Dynamic Isotope Effect[J]. University Chemistry, ;2024, 39(8): 403-410. doi: 10.3866/PKU.DXHX202311093 shu

Basic Theory and Competitive Exam Analysis of Dynamic Isotope Effect

Yaling Chen

Shenzhen Middle School, Shenzhen 518001, Guangdong Province, China

Received Date: 29 November 2023
Revised Date: 2 February 2024

Kinetic isotope effect (KIE) has emerged as a new topic in chemistry competitions both domestically and internationally in recent years. This paper elucidates the origins of first-order and second-order KIE, starting from the perspective of classical transition state theory, based on the potential energy curve and zero-point vibration energy. The role of KIE in the study of reaction mechanisms is briefly discussed. By analyzing relevant exam questions from both domestic and international chemistry competitions, the examination perspectives on KIE are identified, highlighting the continuity between domestic and international competitions. Finally, this paper offers reflections and suggestions for teaching KIE in the context of competitive exams, providing valuable insights and references for educators involved in competition training.
- Kinetic isotope effect,
- Chemistry competition,
- Question analysis
1. [1]
  Bigeleisen, J.; Mayer, M. G. J. Chem. Phys. 1947, 15 (5), 261.
2. [2]
3. [3]
4. [4]
5. [5]
  Clayden; Greeves; Warren; Wothers. Organic Chemistry; Oxford University Press: New York, USA, 2001; pp. 1080–1101.
6. [6]
  Westheimer, F. H.; Nicolaides, N. J. Am. Chem. Soc. 1949, 71 (1), 25.
7. [7]
  Storer, J. W.; Raimondi, L.; Houk, K. N. J. Am. Chem. Soc. 1994, 116 (21), 9675.
8. [8]
  Delmonte, A. J.; Haller, J.; Houk, K. N. J. Am. Chem. Soc. 1997, 119 (41), 9907.
9. [9]
  Lee, I. Chem. Soc. Rev. 1995, 24 (3), 223.
10. [10]
  Lu, L.; Liu, H.; Hua, R. Org. Lett. 2018, 20 (11), 3197.
11. [11]
1. [1]
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2. [2]
  Zhilei Yin , Xinyu Song , Xuan Sun , Zhao Jin , Jin Zhang , Xuemei Ma , Bin Ge , Qisheng Song . Analysis of Inorganic and Analytical Chemistry Experiment in the 13th National Undergraduate Chemistry Experiment Competition Finals. University Chemistry, 2025, 40(11): 416-420. doi: 10.12461/PKU.DXHX202412138
3. [3]
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4. [4]
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17. [17]
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19. [19]
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